NARF_DROER
ID NARF_DROER Reviewed; 477 AA.
AC B3NKH7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GG21400;
GN ORFNames=GG21400;
OS Drosophila erecta (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7220;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14021-0224.01;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH954179; EDV54281.1; -; Genomic_DNA.
DR RefSeq; XP_001973881.1; XM_001973845.2.
DR AlphaFoldDB; B3NKH7; -.
DR SMR; B3NKH7; -.
DR STRING; 7220.FBpp0139946; -.
DR EnsemblMetazoa; FBtr0141454; FBpp0139946; FBgn0113579.
DR GeneID; 6548517; -.
DR KEGG; der:6548517; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR OMA; PHEQRAW; -.
DR OrthoDB; 705416at2759; -.
DR PhylomeDB; B3NKH7; -.
DR Proteomes; UP000008711; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding.
FT CHAIN 1..477
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GG21400"
FT /id="PRO_0000383700"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 477 AA; 54226 MW; 83D52D0BAC9F8ED4 CRC64;
MSGLSRALQL TDIDDFITPS QMCIKPVKID KAKSKTGAKI MIKDDSCFEE SESGKKKLNK
VEITLQDCLA CSGCITSAEG VLITQQSQEE LLRVLQENLT KKATEDWGNV RTIVFTIATQ
PLLSLAHRYQ IGVEDSARHL AGYFRSLGAD YVLSTKVADD IALLECRQEF VERYRENENL
TMLSSSCPGW VCYAEKTHGN FILPYISTTR SPQQIMGVLV KHVFAEKLNV PASQIYHVTV
MPCYDKKLEA SREDFFSTAN NSRDVDCVIT SVEVEQLLSE SQRTLAQYDP VDLDWPWSNV
PPDFMVWAHE KTLSGGYAEH IFKFAAKELF NEVPRSELEF KQLKNRDFRE IILKKNGNTV
LKFAIANGFR NIQNLVHKLK RGKVSNYHFV EVMACPSGCI NGGAQIRPTT GQHVRELTRK
LEELYHNLPQ SDPENSLTKL IYTDFLDGFQ TEKSYELLHT RYHDVVSELS KSLNINW
