NARF_DROMO
ID NARF_DROMO Reviewed; 476 AA.
AC B4KFU7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GI11683;
GN ORFNames=GI11683;
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH933807; EDW12073.1; -; Genomic_DNA.
DR RefSeq; XP_002002631.1; XM_002002595.2.
DR AlphaFoldDB; B4KFU7; -.
DR SMR; B4KFU7; -.
DR STRING; 7230.FBpp0160900; -.
DR EnsemblMetazoa; FBtr0162408; FBpp0160900; FBgn0134442.
DR GeneID; 6576643; -.
DR KEGG; dmo:Dmoj_GI11683; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR InParanoid; B4KFU7; -.
DR OMA; PHEQRAW; -.
DR OrthoDB; 705416at2759; -.
DR PhylomeDB; B4KFU7; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..476
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GI11683"
FT /id="PRO_0000383703"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 476 AA; 53707 MW; 0E5F2D0BB45F1A30 CRC64;
MSRFSGALQL TDLDDFITPS QECIKPVTID KTKSKTGSKI TVQADGYYEE SESGKQKLQK
VEITLQDCLA CSGCITSAEG VLITQQSQEE LLKVLRENER LKASGDSDKV RTIVFTIAVQ
PLISLAHRFE LGVEEAARHL SGYLRQLGAD YVLSTKIADD LALLECRQEF VERYRDNADL
SMLSSSCPGW VCYAEKTHGN FILPHIATTR SPQQIMGVLV KQRLAEKLGV SGSRIYHVTV
MPCYDKKLEA SREDFYSEVN SSRDVDCVIT SIEVEQMLQT EEQTLQQFAP SDMDWPWTDQ
PPEAMVWAHE STMSGGYAEH IYKYAARELF NEETPNELQF KALRNRDFSE ISLEKDGKIV
LKFAIANGFR NIQNLMQKLK RGKGPGYHFV EVMACPSGCI NGGAQVRPTT GQHVRELTQQ
LEELYKQLPR SNPDNAHTKH IYTDFLDGTQ TDKSQSLLHT SYHAVEKLNT ALNIKW
