NARF_DROPE
ID NARF_DROPE Reviewed; 477 AA.
AC B4GXC8;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GL21135;
GN ORFNames=GL21135;
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH479195; EDW27239.1; -; Genomic_DNA.
DR RefSeq; XP_002023111.1; XM_002023075.1.
DR AlphaFoldDB; B4GXC8; -.
DR SMR; B4GXC8; -.
DR STRING; 7234.FBpp0185242; -.
DR EnsemblMetazoa; FBtr0186750; FBpp0185242; FBgn0158729.
DR GeneID; 6597973; -.
DR KEGG; dpe:6597973; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR OMA; PHEQRAW; -.
DR PhylomeDB; B4GXC8; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..477
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GL21135"
FT /id="PRO_0000383704"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 69
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 72
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 75
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 188
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 244
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 396
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 400
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 477 AA; 54068 MW; 5B5EEBBC3E73F7B4 CRC64;
MSRFSGALQL TDLDDFITPS QECIKPVTVD KTATSKTGAK ITVQEDGYYE ESESGKQKLQ
KVEITLQDCL ACSGCITSAE SVLITQQSEE ELLKVLRENA KVKATGDMEQ VRTIVFTIAT
QPLLSLAHRY QLSAEETARH LAGYFRSLGV DYVLCTKVAD DLALLECQQE FVERYRDNEE
LTMLSSSCPG WVCYAEKTHG NFILPYIATT RSPQQIMGVL VKQFLAEKLN IPGSRIYHVT
VMPCYDKKLE ASRMDFYSEV NESRDVDCVI TSVEVEQMLN EDERSLSEHE ASDLDWPWSE
QRPESMVWSH EATLSGGYAE HIFKFAAKEL FNEAPPTELS FKQLRNRDFR EISLEKDDKT
VLKFAIANGF RNIQNLVQKL KRGKGASYHF VEVMACPSGC INGGAQVRPT TGQHVRELTQ
QLEELYKKLP RSQPDNAHTK LIYRDFLDGS HTDKSNELLH TSYHAVEKLS TALNIKW
