NARF_DROSE
ID NARF_DROSE Reviewed; 477 AA.
AC B4IMH3;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GM20417;
GN ORFNames=GM20417;
OS Drosophila sechellia (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7238;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rob3c / Tucson 14021-0248.25;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDW46318.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CH480997; EDW46318.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_002044933.1; XM_002044897.1.
DR AlphaFoldDB; B4IMH3; -.
DR SMR; B4IMH3; -.
DR STRING; 7238.B4IMH3; -.
DR Proteomes; UP000001292; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..477
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GM20417"
FT /id="PRO_0000383706"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 477 AA; 54593 MW; 74F30A007C4084A6 CRC64;
MSRWSTALQL TDIDDFITPS QICIKPVQID KARSKTGAKI KIKGDSCFEE SESGNLKLNK
VDISLQDCLA CSGCITSAEE VLITQQSQEE LLKILQENSK NKASEDWDNV RTIVITLATQ
PLLSLAHRYQ IGVEDAARHL NGYFRSLGAD YVLSTKVADD IALLECRQEF VDRYRENENL
TMLSSSCPGW VCYAEKTHGN FILPYVSTTR SPQQIMGVLV KQILADKINV PASRIYHVTV
MPCYDKKLEA SREDFFSKAN NSRDVDCVIT SVEVEQLLSE AQRPLSQYDL FDLDWPWSNV
RPEFMVWAHE KTQSGGYAEH IFKFAAKHIF NEDLTTELEF KQLKNRDFRE IILKQNGKTV
LKFAIANGFR NIQNLVQKLK REKLSNYHFV EVMACPSGCI NGGAQIRPTT GQHVRELTRK
LEELYHNLPR SEPENSLTKH IYNDFLDGFQ TDKSYEMLHT RYHDVVSDLS ISLNINW
