NARF_DROVI
ID NARF_DROVI Reviewed; 476 AA.
AC B4LQR5;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GJ13047;
GN ORFNames=GJ13047;
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH940649; EDW63449.1; -; Genomic_DNA.
DR RefSeq; XP_002051294.1; XM_002051258.2.
DR AlphaFoldDB; B4LQR5; -.
DR SMR; B4LQR5; -.
DR STRING; 7244.FBpp0227464; -.
DR EnsemblMetazoa; FBtr0228972; FBpp0227464; FBgn0200281.
DR GeneID; 6627489; -.
DR KEGG; dvi:6627489; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR InParanoid; B4LQR5; -.
DR OMA; PHEQRAW; -.
DR OrthoDB; 705416at2759; -.
DR PhylomeDB; B4LQR5; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..476
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GJ13047"
FT /id="PRO_0000383708"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 476 AA; 53663 MW; 6D5D80447F19E6BE CRC64;
MSRFSGALQL TDLDDFITPS QECIKPVMID KTKSKTGAKI TVQADGYYEQ SESGKQKLQK
VEITLQDCLA CSGCITSAEG VLITQQSQEE LLKVLRENQT LKASGDNDQV RTIVFTISVQ
PLLSLAHRYD LGVEEASRYL AGYLRQLGAD YVLCTKIADD LALLECRQEF VERFRDNAEL
SMLSSSCPGW VCYAEKTHGN FILPHIATTR SPQQIMGVLV KQLLAEKLGV PGSRIYHATI
MPCYDKKLEA SREDFYSEVN GSRDVDCVIT SIEVEQMLQA EEQTLQQFEP SDIDWPWTDQ
QPEFPVWAHE ATMSGGYAEH IFKYAAKELF SEETPNELQF KALRNRDFSE ISLEKDGKTV
LKFAIANGFR NIQNLVQKLK RGKGPGYHFV EVMACPSGCI NGGAQVRPTT GQHVRELTQQ
LEELYKQLPR SNPDNSYTKQ IYTDFLDGAH TDKSLELLHT SYHAVEKLNT ALNIKW
