NARF_DROWI
ID NARF_DROWI Reviewed; 477 AA.
AC B4MUM8;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GK14772;
GN ORFNames=GK14772;
OS Drosophila willistoni (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7260;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14030-0811.24;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH963857; EDW76223.1; -; Genomic_DNA.
DR RefSeq; XP_002065237.1; XM_002065201.2.
DR AlphaFoldDB; B4MUM8; -.
DR SMR; B4MUM8; -.
DR STRING; 7260.FBpp0243915; -.
DR EnsemblMetazoa; FBtr0245423; FBpp0243915; FBgn0216777.
DR GeneID; 6641817; -.
DR KEGG; dwi:6641817; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR InParanoid; B4MUM8; -.
DR OMA; PHEQRAW; -.
DR OrthoDB; 705416at2759; -.
DR PhylomeDB; B4MUM8; -.
DR Proteomes; UP000007798; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..477
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GK14772"
FT /id="PRO_0000383709"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 69
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 72
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 75
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 188
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 244
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 396
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 400
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 477 AA; 54233 MW; 3C1ECAF1F594CB71 CRC64;
MSRFSGALQL TDLDDFITPS QECIKPVTID KTKSKTGAKI TVQEDGYYEE SEESGKQKLQ
KVEITLQDCL ACSGCITSAE GVLITQQSQE ELLKVLRENQ KLKATGDNDL VQTIVFTISM
QPILSLAHRY QLSVEETARH LSGYFRNLGA DYVLCTKVAD DLALIECRQE FVERFRDKED
LTMLSSSCPG WVCYAEKTHG NFILPYIATT RSPQQIMGVL VKHFLAEKFN VPGSRIYHAT
VMPCYDKKLE ASREDFYSEV NGSRDVDCVI TSIEVEQMLM EDERSLSQHE PVDLDWPWTD
QRPESMIWAH EATMSGGYAE HIFKYAAKEL FSEDTDNELK FKQLRNRDFR EISLEKDDKT
VLKFAIANGF RNIQNLVQKL KRGKGANYHF VEVMACPSGC INGGAQVRPT TGQHVRELTQ
QLEELYKKLP ISQPDNSHTK AIYGDFLDGA HTDKSHDLLH TSYHAVEKLN TALNIKW
