NARF_DROYA
ID NARF_DROYA Reviewed; 477 AA.
AC B4ISL0;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Probable cytosolic Fe-S cluster assembly factor GE22682;
GN ORFNames=GE22682;
OS Drosophila yakuba (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tai18E2 / Tucson 14021-0261.01;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC assembly machinery. Required for maturation of extramitochondrial Fe/S
CC proteins (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR EMBL; CH891577; EDW99365.1; -; Genomic_DNA.
DR RefSeq; XP_002085972.1; XM_002085936.2.
DR AlphaFoldDB; B4ISL0; -.
DR SMR; B4ISL0; -.
DR STRING; 7245.FBpp0267692; -.
DR EnsemblMetazoa; FBtr0269200; FBpp0267692; FBgn0239891.
DR GeneID; 6539081; -.
DR KEGG; dya:Dyak_GE22682; -.
DR eggNOG; KOG2439; Eukaryota.
DR HOGENOM; CLU_018240_0_0_1; -.
DR OMA; PHEQRAW; -.
DR PhylomeDB; B4ISL0; -.
DR Proteomes; UP000002282; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF53920; SSF53920; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding.
FT CHAIN 1..477
FT /note="Probable cytosolic Fe-S cluster assembly factor
FT GE22682"
FT /id="PRO_0000383710"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 68
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 71
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 74
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000255"
FT BINDING 187
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 243
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 395
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
FT BINDING 399
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000255"
SQ SEQUENCE 477 AA; 54251 MW; 437FB8477A0DFAEC CRC64;
MSRLSRALQL TDIDDFITPS QICIKPVEID KARSKTGAKI KIKGDSCFEE SESGKQKLNK
VEITLQDCLA CSGCITSAEG VLITQQSQEE LLRVLQENSK KKATEDWDNV RTIVFSVATQ
PLLSLAHRYQ IGVEDAARHL AGYFRSLGGN YVLSTKVADD IALLECRQEF VERYRENENL
TMLSSSCPGW VCYAEKTHGN FILPYVSTTR SPQQIMGVLV KHILAEKLNI PASRIYHVTV
MPCYDKKLEA SRDDFFSKTN NSRDVDCVIT SVEVEQLLGE AQRTLSQFDP LDLDWPWSNV
RPDLMVWAHE KTLSGGYAEH VFKFAAKQIF NEVPTNELEF KQLKNRDFRE IILKKNGNTV
LKFAIANGFR NIQNMVQKLK RGKVSNYHFV EVMACPSGCI NGGAQIRPTT GQHVRELTRK
LEELYHNLPL SEPENSLTKH IYKDFLDGFQ TEKSYELLHT SYHDVVSELS ISLNINW
