ID   NARF_NEMVE              Reviewed;         441 AA.
AC   A7SDA8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable cytosolic Fe-S cluster assembly factor v1g210509;
GN   ORFNames=v1g210509;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein
CC       assembly machinery. Required for maturation of extramitochondrial Fe/S
CC       proteins (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NARF family. {ECO:0000305}.
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DR   EMBL; DS469629; EDO38275.1; -; Genomic_DNA.
DR   RefSeq; XP_001630338.1; XM_001630288.1.
DR   AlphaFoldDB; A7SDA8; -.
DR   SMR; A7SDA8; -.
DR   STRING; 45351.EDO38275; -.
DR   EnsemblMetazoa; EDO38275; EDO38275; NEMVEDRAFT_v1g210509.
DR   eggNOG; KOG2439; Eukaryota.
DR   HOGENOM; CLU_018240_0_0_1; -.
DR   InParanoid; A7SDA8; -.
DR   OMA; PHEQRAW; -.
DR   OrthoDB; 705416at2759; -.
DR   PhylomeDB; A7SDA8; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
DR   InterPro; IPR009016; Fe_hydrogenase.
DR   InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR   Pfam; PF02906; Fe_hyd_lg_C; 1.
DR   SUPFAM; SSF53920; SSF53920; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT   CHAIN           1..441
FT                   /note="Probable cytosolic Fe-S cluster assembly factor
FT                   v1g210509"
FT                   /id="PRO_0000383711"
FT   BINDING         24
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         72
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         75
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         78
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255"
FT   BINDING         196
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         252
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
FT   BINDING         401
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   441 AA;  49099 MW;  425B994BD64FE6D1 CRC64;
     MAAHFSGALQ LTNLDDFITP SQECIKPVKI EKKPGAKGLA KIKIESDGSY VQLSEDGGKS
     KLQKAEITLN DCLACSGCIT TAESVLITQQ SQDELFKILD SNRKLVKEGK GDVQKLVVIS
     ISPQSRASIA AKFNLTINDA AKKLSAFFKQ LGVHYVFDTT FARDFSLAES QREFVRRFRA
     YQQGDEGCTP MLASACPGWM CYAEKTHGDY ILPYISSTKS PQQIMGSLVK DHLASVVGKS
     PDSVYHVCVM PCFDKKLEAS RDDFYNDMYS TRDVDCVIST VEVETMIQDH CPDFNSIDPV
     ELDKLYCSSD SGDFFGHSGG GSGGFLEHIF KYASRELFDE KVDVLTYKTL RNKDFREVTL
     QVDGKDVLKF AAAYGFRNIQ NLVQKLKRGK SPYHFVEVMA CPSGLKFLAQ DLFGPTFYPT
     LEPRSLEKNV QQKNGVSCIF I