ID   NART_STAES              Reviewed;         387 AA.
AC   Q8CN76;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Probable nitrate transporter NarT;
GN   Name=narT; Synonyms=narK; OrderedLocusNames=SE_1968;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Probably required for nitrate uptake under anoxic conditions.
CC       Also possibly involved in excretion of nitrite produced by the
CC       dissimilatory reduction of nitrate (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Positively regulated by the two-component system NreB/NreC.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Nitrate/nitrite porter (TC 2.A.1.8) family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05609.1; -; Genomic_DNA.
DR   RefSeq; NP_765523.1; NC_004461.1.
DR   RefSeq; WP_002470210.1; NZ_WBME01000017.1.
DR   AlphaFoldDB; Q8CN76; -.
DR   SMR; Q8CN76; -.
DR   STRING; 176280.SE_1968; -.
DR   EnsemblBacteria; AAO05609; AAO05609; SE_1968.
DR   GeneID; 50017938; -.
DR   KEGG; sep:SE_1968; -.
DR   PATRIC; fig|176280.10.peg.1921; -.
DR   eggNOG; COG2223; Bacteria.
DR   HOGENOM; CLU_001265_14_0_9; -.
DR   OMA; DAWWFMF; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   CDD; cd17341; MFS_NRT2_like; 1.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR044772; NO3_transporter.
DR   PANTHER; PTHR23515; PTHR23515; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Nitrate assimilation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..387
FT                   /note="Probable nitrate transporter NarT"
FT                   /id="PRO_0000349401"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        294..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   387 AA;  41589 MW;  6826ED38A70E5447 CRC64;
     MNMKKGVSQL TLQTLSLVAG FMAWSIISPL MPFISQDVDI SPGQISVILA IPVILGSVLR
     VPFGYLTNIV GAKWVFFWSF IVLLLPIFLL GQAQSPGMLM LSGFFLGIGG AIFSVGVTSV
     PKYFSKDKVG LANGIYGVGN IGTAVSSFCA PVLAGAIGWQ NTVRSYLIIL SIFAILMFFL
     GDKNEPKVKI PLMAQVKDLS KNYKLYYLSL WYFITFGAFV AFGIFLPNFL VDHFSIDKVD
     AGIRSGIFIA LATFLRPVGG VIGDKFNAVQ ALIIDFVIMI IGALILSLSS HIVLFTIGCL
     AISICAGIGN GLIFKLVPSY FSKEAGSANG IVSMMGGLGG FFPPLVITFV TSITGSSHLA
     FFFLAIFGVI ALITMIHLNK KEKAIRI