ID   NART_STAHJ              Reviewed;         385 AA.
AC   Q4L8Q5;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Probable nitrate transporter NarT;
GN   Name=narT; Synonyms=narK; OrderedLocusNames=SH0661;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Probably required for nitrate uptake under anoxic conditions.
CC       Also possibly involved in excretion of nitrite produced by the
CC       dissimilatory reduction of nitrate (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Positively regulated by the two-component system NreB/NreC.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Nitrate/nitrite porter (TC 2.A.1.8) family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE03970.1; -; Genomic_DNA.
DR   RefSeq; WP_011274986.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8Q5; -.
DR   SMR; Q4L8Q5; -.
DR   STRING; 279808.SH0661; -.
DR   EnsemblBacteria; BAE03970; BAE03970; SH0661.
DR   GeneID; 58063148; -.
DR   KEGG; sha:SH0661; -.
DR   eggNOG; COG2223; Bacteria.
DR   HOGENOM; CLU_001265_14_0_9; -.
DR   OMA; DAWWFMF; -.
DR   OrthoDB; 1217595at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   CDD; cd17341; MFS_NRT2_like; 1.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR044772; NO3_transporter.
DR   PANTHER; PTHR23515; PTHR23515; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Nitrate assimilation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..385
FT                   /note="Probable nitrate transporter NarT"
FT                   /id="PRO_0000349403"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        330..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   385 AA;  41428 MW;  A9A316A27893C139 CRC64;
     MYKTKGGFQL TLQTLSLVVG FMAWSIISPL MPYISQDVKV NPGQLSIILA IPVILGSILR
     VPFGYLTNII GAKWVFFCSF VILLFPIFFL GQAQTPGMLM LSGFFLGVGG AIFSVGVTSV
     PKYFSKDKVG LANGIYGMGN IGTAVSSFLA PPIAGIIGWQ TTVRSYLIII AIFAILMFIF
     GDKNEPKVKV PLASQFKKLS SNYKLYYLSL WYFITFGAFV AFGLFLPNYL VNNFGIDKVD
     AGIRSGVFIA LATFLRPIGG ILGDKFNAVK VLMIDFIIMI VGAVILGISS HIALFTIGCL
     TISICAGLGN GLIFKLVPSY FAKESGAANG IVSMMGGLGG FFPPLVITYV TGLTGSSHLA
     FILLAIFGVL AFITMGHLYK KEYAK