ID   NAT14_BOVIN             Reviewed;         206 AA.
AC   Q3MHZ1;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Probable N-acetyltransferase 14;
DE            EC=2.3.1.- {ECO:0000305};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable acetyltransferase. {ECO:0000305}.
CC   -!- FUNCTION: May act as a transcription factor regulating the expression
CC       of coproporphyrinogen oxidase by binding to a promoter regulatory
CC       element. {ECO:0000250|UniProtKB:Q8WUY8}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the camello family. {ECO:0000305}.
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DR   EMBL; BC104515; AAI04516.1; -; mRNA.
DR   RefSeq; NP_001032322.1; NM_001037245.1.
DR   RefSeq; XP_005219762.1; XM_005219705.3.
DR   RefSeq; XP_010813786.1; XM_010815484.2.
DR   AlphaFoldDB; Q3MHZ1; -.
DR   STRING; 9913.ENSBTAP00000025357; -.
DR   PaxDb; Q3MHZ1; -.
DR   PRIDE; Q3MHZ1; -.
DR   Ensembl; ENSBTAT00000025357; ENSBTAP00000025357; ENSBTAG00000019051.
DR   GeneID; 532809; -.
DR   KEGG; bta:532809; -.
DR   CTD; 57106; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019051; -.
DR   eggNOG; ENOG502RYNT; Eukaryota.
DR   GeneTree; ENSGT00950000182932; -.
DR   HOGENOM; CLU_127402_0_0_1; -.
DR   InParanoid; Q3MHZ1; -.
DR   OMA; RWHRRQG; -.
DR   OrthoDB; 1543328at2759; -.
DR   TreeFam; TF336981; -.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000019051; Expressed in retina and 101 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IBA:GO_Central.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   2: Evidence at transcript level;
KW   Activator; Acyltransferase; DNA-binding; Membrane; Reference proteome;
KW   Transcription; Transcription regulation; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..206
FT                   /note="Probable N-acetyltransferase 14"
FT                   /id="PRO_0000307785"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          55..206
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   206 AA;  21734 MW;  9B861D6F9A58D375 CRC64;
     MAPSHLSVRE MREDEKPLVL EMLKAGVKDT ENRVALHALT RPPALLLLAA ASSGLRFVLA
     SFALALLLPV FLAVAAMKLG LRARWGSLPP PGGLGGPWVA VRGSGDVCGV LALAPGSSAG
     DGARVTRLSV SRWHRRRGVG RRLLAFAESR ARAWAGGMGE PRARLVVPVA VAAWGVAGML
     EGCGYQAEGS WGCMGYTLVR EFSKEL