ID   NAT14_DANRE             Reviewed;         280 AA.
AC   Q0P4A4;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Probable N-acetyltransferase 14;
DE            EC=2.3.1.- {ECO:0000305};
GN   Name=nat14; ORFNames=zgc:153234;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable acetyltransferase. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the camello family. {ECO:0000305}.
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DR   EMBL; BC122198; AAI22199.1; -; mRNA.
DR   RefSeq; NP_001038809.1; NM_001045344.1.
DR   AlphaFoldDB; Q0P4A4; -.
DR   SMR; Q0P4A4; -.
DR   STRING; 7955.ENSDARP00000111670; -.
DR   PaxDb; Q0P4A4; -.
DR   PRIDE; Q0P4A4; -.
DR   GeneID; 751624; -.
DR   KEGG; dre:751624; -.
DR   CTD; 57106; -.
DR   ZFIN; ZDB-GENE-060825-15; nat14.
DR   eggNOG; ENOG502RYNT; Eukaryota.
DR   InParanoid; Q0P4A4; -.
DR   OrthoDB; 1543328at2759; -.
DR   PRO; PR:Q0P4A4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IBA:GO_Central.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Membrane; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..280
FT                   /note="Probable N-acetyltransferase 14"
FT                   /id="PRO_0000307789"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          116..273
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
FT   REGION          111..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        131..152
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   280 AA;  31818 MW;  2D379B1C1D36E362 CRC64;
     MVRLDLADVV LRRMQEKDIE AVKALIKEGC EGTENRLILH LLTRPLALLL LAILSSILRC
     VLHSFVLALV IPVFISVIYL KLTIPRSAGI LGSCRPYWDY IGSSYHADTE PDLPNPHLGR
     AKLTTNQEKT RRRKKAKEKE KMNESEQVDE DELKQRAKVA GEVWVADSDG EIVGCVARDG
     WSRDGVCRVC RLVVQCWYRR EGLGRLLVQG LESRTKQKGV CRVYAHVPIP SKVGEAFFRR
     LGYRLQGETA GIEEEEEDDY EDPEKGWLGY PLTKVFVKDL