ID   NAT14_MACFA             Reviewed;         206 AA.
AC   Q9N0D0;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Probable N-acetyltransferase 14;
DE            EC=2.3.1.- {ECO:0000305};
GN   Name=NAT14; ORFNames=QccE-12666;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirai M., Terao K.,
RA   Suzuki Y., Sugano S., Hashimoto K.;
RT   "Isolation of full-length cDNA clones from macaque brain cDNA libraries.";
RL   Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable acetyltransferase. {ECO:0000305}.
CC   -!- FUNCTION: May act as a transcription factor regulating the expression
CC       of coproporphyrinogen oxidase by binding to a promoter regulatory
CC       element. {ECO:0000250|UniProtKB:Q8WUY8}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the camello family. {ECO:0000305}.
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DR   EMBL; AB046000; BAB01582.1; -; mRNA.
DR   RefSeq; NP_001306464.1; NM_001319535.1.
DR   RefSeq; XP_015297025.1; XM_015441539.1.
DR   AlphaFoldDB; Q9N0D0; -.
DR   STRING; 9541.XP_005590758.1; -.
DR   GeneID; 102123243; -.
DR   CTD; 57106; -.
DR   eggNOG; ENOG502RYNT; Eukaryota.
DR   OrthoDB; 1318443at2759; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   2: Evidence at transcript level;
KW   Activator; Acyltransferase; DNA-binding; Membrane; Reference proteome;
KW   Transcription; Transcription regulation; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..206
FT                   /note="Probable N-acetyltransferase 14"
FT                   /id="PRO_0000307787"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          55..206
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   206 AA;  21662 MW;  713BEF1FE62193A8 CRC64;
     MAPSHLSVRE VREDEKPLVL EMLKAGVKDT ENRVALHALT RPPALLLLAA ASSGLRFVLA
     SFALALLLPV FLAVTAVKLG LRARWGSLPP PGGLGGPWVA VRGSGDVCGV LALAPGTNAG
     DGARVTRLSV SRWHRRRGVG RRLLAFAEAR ARAWAGGMGE PRARLVVPVA VAAWGVAGML
     EGCGYQAEGG WGCLGYTLVR EFSKDL