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NBDY_PONAB
ID   NBDY_PONAB              Reviewed;          68 AA.
AC   Q5RDV1;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Negative regulator of P-body association {ECO:0000250|UniProtKB:A0A0U1RR68};
DE   AltName: Full=P-body dissociating protein {ECO:0000250|UniProtKB:A0A0U1RR68};
DE   AltName: Full=Protein NoBody {ECO:0000250|UniProtKB:A0A0U1RR68};
GN   Name=NBDY {ECO:0000250|UniProtKB:A0A0U1RR68};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Promotes dispersal of P-body components and is likely to play
CC       a role in the mRNA decapping process.
CC       {ECO:0000250|UniProtKB:A0A0U1RR68}.
CC   -!- SUBUNIT: Interacts with mRNA decapping proteins DCP1A, DCP2 and EDC4.
CC       {ECO:0000250|UniProtKB:A0A0U1RR68}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC       {ECO:0000250|UniProtKB:A0A0U1RR68}. Note=Localizes to P-bodies at low
CC       concentrations without dissociating them.
CC       {ECO:0000250|UniProtKB:A0A0U1RR68}.
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DR   EMBL; CR857793; CAH90056.1; -; mRNA.
DR   AlphaFoldDB; Q5RDV1; -.
DR   Ensembl; ENSPPYT00000060833; ENSPPYP00000033482; ENSPPYG00000031732.
DR   GeneTree; ENSGT00390000004891; -.
DR   HOGENOM; CLU_2793310_0_0_1; -.
DR   InParanoid; Q5RDV1; -.
DR   OMA; NTRETRP; -.
DR   TreeFam; TF353536; -.
DR   Proteomes; UP000001595; Chromosome X.
DR   GO; GO:0000932; C:P-body; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0010607; P:negative regulation of cytoplasmic mRNA processing body assembly; ISS:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; ISS:UniProtKB.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Reference proteome.
FT   CHAIN           1..68
FT                   /note="Negative regulator of P-body association"
FT                   /id="PRO_0000342660"
FT   REGION          1..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            30
FT                   /note="Required for interaction with EDC4"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0U1RR68"
FT   SITE            34
FT                   /note="Required for interaction with EDC4"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0U1RR68"
SQ   SEQUENCE   68 AA;  7025 MW;  FA372C7380B65853 CRC64;
     MGDQPCASGR STLPPGNARE AKPPKKRCLL APRWDYPEGT PNGGSTTLPS APPPASAGLK
     SHPPPPEK
 
 
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