ID   NBPF5_HUMAN             Reviewed;         351 AA.
AC   Q86XG9;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Putative neuroblastoma breakpoint family member 5;
GN   Name=NBPF5P; Synonyms=NBPF5;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   TISSUE SPECIFICITY.
RX   PubMed=16079250; DOI=10.1093/molbev/msi222;
RA   Vandepoele K., Van Roy N., Staes K., Speleman F., van Roy F.;
RT   "A novel gene family NBPF: intricate structure generated by gene
RT   duplications during primate evolution.";
RL   Mol. Biol. Evol. 22:2265-2274(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in brain and medulla.
CC       {ECO:0000269|PubMed:16079250}.
CC   -!- MISCELLANEOUS: Encoded by one of the numerous copies of NBPF genes
CC       clustered in the p36, p12 and q21 region of the chromosome 1.
CC   -!- SIMILARITY: Belongs to the NBPF family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH43522.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC043522; AAH43522.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q86XG9; -.
DR   BioMuta; HGNC:24491; -.
DR   DMDM; 152123237; -.
DR   PRIDE; Q86XG9; -.
DR   GeneCards; NBPF5P; -.
DR   HGNC; HGNC:24491; NBPF5P.
DR   MIM; 613995; gene.
DR   neXtProt; NX_Q86XG9; -.
DR   InParanoid; Q86XG9; -.
DR   Pharos; Q86XG9; Tdark.
DR   PRO; PR:Q86XG9; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q86XG9; protein.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010630; Olduvai_dom.
DR   Pfam; PF06758; Olduvai; 1.
DR   SMART; SM01148; DUF1220; 2.
DR   PROSITE; PS51316; ODV; 1.
PE   5: Uncertain;
KW   Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..351
FT                   /note="Putative neuroblastoma breakpoint family member 5"
FT                   /id="PRO_0000288040"
FT   DOMAIN          174..261
FT                   /note="Olduvai"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00647"
FT   REGION          157..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          10..43
FT                   /evidence="ECO:0000255"
FT   COILED          69..115
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        166..181
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..228
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..285
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  40546 MW;  7F9449EB9DE375C4 CRC64;
     MVVSADPLSS ERAEMNILEI NQELRSQLAE SNQQFRDLKE KFLITQATAY SLANQLKKYK
     CEEYKDIIDS VLRDELQSME KLAEKLRQAE ELRQYKALVH SQAKELTQLR EKLREGRDAS
     RWLNKHLKTL LTPDDPDKSQ GQDLREQLAE GHRLAEHLVH KLSPENDEDE DEDEDDKDEE
     VEKVQESPAP REVQKTEEKE VPQDSLEECA VTCSNSHNPS NSNQPHRSTK ITFKEHEVDS
     ALVVESEHPH DEEEEALNIP PENQNDHEEE EGKAPVPPRH HDKSNSYRHR EVSFLALDEQ
     KVCSAQDVAR DYSNPKWDET SLGFLDTPLA RRESVALKGR TRSWQHSSHA N