NC2B_ARATH
ID NC2B_ARATH Reviewed; 159 AA.
AC P49592;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Protein Dr1 homolog;
DE AltName: Full=Negative cofactor 2-beta homolog;
DE Short=NC2-beta homolog;
GN Name=DR1; OrderedLocusNames=At5g23090; ORFNames=MYJ24.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=7816619; DOI=10.1093/nar/22.24.5296;
RA Kuromori T., Yamamoto M.;
RT "Cloning of cDNAs from Arabidopsis thaliana that encode putative protein
RT phosphatase 2C and a human Dr1-like protein by transformation of a fission
RT yeast mutant.";
RL Nucleic Acids Res. 22:5296-5301(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- INTERACTION:
CC P49592; F4K162: At5g19490; NbExp=3; IntAct=EBI-15193559, EBI-15191807;
CC P49592; Q9LHG0: NF-YC11; NbExp=3; IntAct=EBI-15193559, EBI-4452389;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=P49592-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the NC2 beta/DR1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D38110; BAA07288.1; -; mRNA.
DR EMBL; AB006708; BAB09826.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93118.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93120.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68726.1; -; Genomic_DNA.
DR EMBL; AY057709; AAL15339.1; -; mRNA.
DR EMBL; AY116960; AAM51594.1; -; mRNA.
DR PIR; S53582; S53582.
DR RefSeq; NP_001330452.1; NM_001343789.1. [P49592-1]
DR RefSeq; NP_851060.1; NM_180729.3. [P49592-1]
DR RefSeq; NP_851061.1; NM_180730.3. [P49592-1]
DR AlphaFoldDB; P49592; -.
DR SMR; P49592; -.
DR BioGRID; 17648; 13.
DR IntAct; P49592; 9.
DR STRING; 3702.AT5G23090.2; -.
DR iPTMnet; P49592; -.
DR PaxDb; P49592; -.
DR PRIDE; P49592; -.
DR EnsemblPlants; AT5G23090.1; AT5G23090.1; AT5G23090. [P49592-1]
DR EnsemblPlants; AT5G23090.2; AT5G23090.2; AT5G23090. [P49592-1]
DR EnsemblPlants; AT5G23090.5; AT5G23090.5; AT5G23090. [P49592-1]
DR GeneID; 832373; -.
DR Gramene; AT5G23090.1; AT5G23090.1; AT5G23090. [P49592-1]
DR Gramene; AT5G23090.2; AT5G23090.2; AT5G23090. [P49592-1]
DR Gramene; AT5G23090.5; AT5G23090.5; AT5G23090. [P49592-1]
DR KEGG; ath:AT5G23090; -.
DR Araport; AT5G23090; -.
DR TAIR; locus:2178307; AT5G23090.
DR eggNOG; KOG0871; Eukaryota.
DR HOGENOM; CLU_066247_11_0_1; -.
DR InParanoid; P49592; -.
DR PhylomeDB; P49592; -.
DR PRO; PR:P49592; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P49592; baseline and differential.
DR Genevisible; P49592; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR044255; Dr1-like.
DR InterPro; IPR009072; Histone-fold.
DR PANTHER; PTHR47173; PTHR47173; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Nucleus; Reference proteome; Transcription.
FT CHAIN 1..159
FT /note="Protein Dr1 homolog"
FT /id="PRO_0000079999"
FT REGION 135..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 17942 MW; B5BCEC9E9BBF54FE CRC64;
MDPMDIVGKS KEDASLPKAT MTKIIKEMLP PDVRVARDAQ DLLIECCVEF INLVSSESND
VCNKEDKRTI APEHVLKALQ VLGFGEYIEE VYAAYEQHKY ETMQDTQRSV KWNPGAQMTE
EEAAAEQQRM FAEARARMNG GVSVPQPEHP ETDQRSPQS
