NCA3_YEAST
ID NCA3_YEAST Reviewed; 337 AA.
AC P46955; D6VW68; E9P8T8;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Beta-glucosidase-like protein NCA3, mitochondrial;
DE Flags: Precursor;
GN Name=NCA3; OrderedLocusNames=YJL116C; ORFNames=J0748;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7586026; DOI=10.1007/bf00311209;
RA Pelissier P., Camougrand N., Velours G., Guerin M.;
RT "NCA3, a nuclear gene involved in the mitochondrial expression of subunits
RT 6 and 8 of the Fo-F1 ATP synthase of S. cerevisiae.";
RL Curr. Genet. 27:409-416(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8948101;
RX DOI=10.1002/(sici)1097-0061(199611)12:14<1471::aid-yea30>3.0.co;2-4;
RA Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.;
RT "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19
RT open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14,
RT RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta
RT elements and a Ty4 transposon.";
RL Yeast 12:1471-1474(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 31-337.
RC STRAIN=S288c / GRF88;
RA Bun-Ya M., Yompakdee C., Shikata K., Ogawa N., Harashima S., Oshima Y.;
RL Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the mitochondrial expression of subunits 6 and 8
CC of the F0-F1 ATP synthase.
CC -!- SUBCELLULAR LOCATION: Mitochondrion.
CC -!- SIMILARITY: Belongs to the SUN family. {ECO:0000305}.
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DR EMBL; L20786; AAC37467.1; -; Genomic_DNA.
DR EMBL; Z49391; CAA89411.1; -; Genomic_DNA.
DR EMBL; AY557880; AAS56206.1; -; Genomic_DNA.
DR EMBL; D63817; BAA09886.1; -; Genomic_DNA.
DR EMBL; BK006943; DAA08684.1; -; Genomic_DNA.
DR PIR; S55932; S55932.
DR RefSeq; NP_012419.1; NM_001181549.1.
DR AlphaFoldDB; P46955; -.
DR BioGRID; 33638; 129.
DR STRING; 4932.YJL116C; -.
DR MaxQB; P46955; -.
DR PaxDb; P46955; -.
DR PRIDE; P46955; -.
DR EnsemblFungi; YJL116C_mRNA; YJL116C; YJL116C.
DR GeneID; 853326; -.
DR KEGG; sce:YJL116C; -.
DR SGD; S000003652; NCA3.
DR VEuPathDB; FungiDB:YJL116C; -.
DR eggNOG; ENOG502QREM; Eukaryota.
DR GeneTree; ENSGT00940000176328; -.
DR HOGENOM; CLU_033459_0_0_1; -.
DR InParanoid; P46955; -.
DR OMA; DNTYCSY; -.
DR BioCyc; YEAST:G3O-31570-MON; -.
DR PRO; PR:P46955; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P46955; protein.
DR GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR GO; GO:0009277; C:fungal-type cell wall; IBA:GO_Central.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0031505; P:fungal-type cell wall organization; IBA:GO_Central.
DR GO; GO:0042776; P:proton motive force-driven mitochondrial ATP synthesis; IGI:SGD.
DR InterPro; IPR005556; SUN.
DR Pfam; PF03856; SUN; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..337
FT /note="Beta-glucosidase-like protein NCA3, mitochondrial"
FT /id="PRO_0000033463"
FT REGION 57..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 292
FT /note="F -> L (in Ref. 5; AAS56206)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 337 AA; 35412 MW; 6888F3D199D8401E CRC64;
MKISAALILS SLSSVAFSAP APAPADSHHE DHHKDEKPAV VTVTQYIDSN AATSTVESAA
TTTTLSSSEK DTSEQKRDGG FQDGTVKCSD FPSVNGIVSL DWLGFGGWAS VMDMDANTSS
ECKDGYYCSY ACEPGMSKTQ WPSDQPSDGK SVGGLYCKNG YLYRTNTDTS DLCSTDETSA
KAINKKSDSI ALCRTDYPGS ENMVIPTVVD GGDSQPISVV DEDTYYQWQG KKTSAQYYIN
NAGVSAEDGC IWGTSGSDVG NWAPLVLGAG STNGETYLSL IPNPNSNQAA NFNVKIVASD
GANVQGSCAY EDGSFTGDGS DGCTVSVLSG SAEFVFY
