ID   NCAP_BUNGE              Reviewed;         233 AA.
AC   P16993;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   29-SEP-2021, entry version 60.
DE   RecName: Full=Nucleoprotein;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=Protein N;
GN   Name=N;
OS   Bunyavirus germiston.
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Ellioviricetes; Bunyavirales; Peribunyaviridae; Orthobunyavirus.
OX   NCBI_TaxID=11574;
OH   NCBI_TaxID=53527; Culex.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3660942; DOI=10.1016/0168-1702(87)90035-9;
RA   Gerbaud S., Vialat P., Pardigon N., Wychowski C., Girard M., Bouloy M.;
RT   "The S segment of the Germiston virus RNA genome can code for three
RT   proteins.";
RL   Virus Res. 8:1-13(1987).
CC   -!- FUNCTION: Encapsidates the genome protecting it from nucleases. The
CC       encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as
CC       template for transcription and replication. Seems to participate in the
CC       nuclear relocalization of host PABP1, thereby inhibiting host cellular
CC       translation (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
CC       genomic RNA. Interacts with host PABP1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Note=Internal protein of virus particle.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative initiation; Named isoforms=2;
CC       Name=N;
CC         IsoId=P16993-1; Sequence=Displayed;
CC       Name=NSS;
CC         IsoId=P16992-1; Sequence=External;
CC   -!- SIMILARITY: Belongs to the orthobunyavirus nucleocapsid protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M19420; AAA87603.1; -; Genomic_RNA.
DR   SMR; P16993; -.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0039657; P:suppression by virus of host gene expression; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.472.180; -; 1.
DR   Gene3D; 1.20.142.20; -; 1.
DR   InterPro; IPR001784; Bunya_nucleocap.
DR   InterPro; IPR043011; Bunya_nucleocap_C.
DR   InterPro; IPR043012; Bunya_nucleocap_N.
DR   Pfam; PF00952; Bunya_nucleocap; 1.
DR   PIRSF; PIRSF003947; N_OrthobunV; 1.
PE   3: Inferred from homology;
KW   Alternative initiation; Capsid protein;
KW   Eukaryotic host gene expression shutoff by virus;
KW   Eukaryotic host translation shutoff by virus; Helical capsid protein;
KW   Host gene expression shutoff by virus; Host-virus interaction;
KW   Ribonucleoprotein; RNA-binding; Viral nucleoprotein; Virion.
FT   CHAIN           1..233
FT                   /note="Nucleoprotein"
FT                   /id="PRO_0000221989"
SQ   SEQUENCE   233 AA;  26703 MW;  56456B22F30E2185 CRC64;
     MLELEFEDVP NNIGSTFDPE SGYTNFQRNY LPGVTLDQIR IFYIKGREIK NSLSKRSEWE
     VTLNLGGWKV PVLNTNFPGN RNNAVPDYGL TFHRISGYLA RYLLGKYLAE TEPEKLIMRT
     KIVNPLAEKN GITWESGPEV YLSFFPGAEM FLGTFRFYPL AIGIYKVQRK EMDPKFLEKT
     MRQRYLGIDA QTWTTTKLGE VEAALKVVSG LGWKKTNVSS AAREFLSKFG IRM