NCAP_CCHFI
ID NCAP_CCHFI Reviewed; 482 AA.
AC P89522;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 02-JUN-2021, entry version 65.
DE RecName: Full=Nucleoprotein;
DE AltName: Full=Nucleocapsid protein;
DE Short=Protein N;
GN Name=N;
OS Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970)
OS (CCHFV).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC Ellioviricetes; Bunyavirales; Nairoviridae; Orthonairovirus.
OX NCBI_TaxID=652961;
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9925; Capra hircus (Goat).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=34625; Hyalomma.
OH NCBI_TaxID=9940; Ovis aries (Sheep).
OH NCBI_TaxID=6941; Rhipicephalus microplus (Cattle tick) (Boophilus microplus).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA Lofts R., Hodgson L., Smith J.F.;
RT "Crimean-Congo hemorrhagic fever virus S segment.";
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Note=Internal protein of
CC virus particle.
CC -!- SIMILARITY: Belongs to the nairovirus nucleocapsid protein family.
CC {ECO:0000305}.
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DR EMBL; U88410; AAB48501.1; -; Genomic_RNA.
DR PDB; 4AQF; X-ray; 3.10 A; A/B/C=1-482.
DR PDB; 4AQG; X-ray; 2.80 A; A=1-482.
DR PDBsum; 4AQF; -.
DR PDBsum; 4AQG; -.
DR SMR; P89522; -.
DR Proteomes; UP000008767; Genome.
DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR003486; Nairo_nucleocap.
DR Pfam; PF02477; Nairo_nucleo; 1.
DR PIRSF; PIRSF003950; N_NairoV; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Helical capsid protein; Reference proteome;
KW Ribonucleoprotein; RNA-binding; Viral nucleoprotein; Virion.
FT CHAIN 1..482
FT /note="Nucleoprotein"
FT /id="PRO_0000406568"
FT HELIX 10..21
FT /evidence="ECO:0007829|PDB:4AQG"
FT STRAND 29..33
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 44..50
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 56..71
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 72..74
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 77..83
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 86..97
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 100..103
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 104..108
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 110..113
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 120..137
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 143..145
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 160..162
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 163..181
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 196..204
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 205..207
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 209..213
FT /evidence="ECO:0007829|PDB:4AQG"
FT STRAND 227..229
FT /evidence="ECO:0007829|PDB:4AQF"
FT HELIX 230..242
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 245..263
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 264..267
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 270..300
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 306..316
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 321..323
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 324..336
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 341..350
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 355..360
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 365..367
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 372..374
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 382..384
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 385..392
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 400..404
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 410..415
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 420..422
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 425..438
FT /evidence="ECO:0007829|PDB:4AQG"
FT TURN 443..445
FT /evidence="ECO:0007829|PDB:4AQG"
FT HELIX 450..460
FT /evidence="ECO:0007829|PDB:4AQG"
FT STRAND 464..466
FT /evidence="ECO:0007829|PDB:4AQF"
SQ SEQUENCE 482 AA; 53891 MW; 3E37B8A17F1B8F5D CRC64;
MENKIEVNNK DEMNRWFEEF KKGNGLVDTF TNSYSFCESV PNLDRFVFQM ASATDDAQKD
SIYASALVEA TKFCAPIYEC AWVSSTGIVK KGLEWFEKNA GTIKSWDESY TELKVDVPKI
EQLTGYQQAA LKWRKDIGFR VNANTAALSN KVLAEYKVPG EIVMSVKEML SDMIRRRNLI
LNRGGDENPR GPVSHEHVDW CREFVKGKYI MAFNPPWGDI NKSGRSGIAL VATGLAKLAE
TEGKGIFDEA KKTVEALNGY LDKHKDEVDR ASADSMITNL LKHIAKAQEL YKNSSALRAQ
SAQIDTAFSS YYWLYKAGVT PETFPTVSQF LFELGKQPRG TKKMKKALLS TPMKWGKKLY
ELFADDSFQQ NRIYMHPAVL TAGRISEMGV CFGTIPVANP DDAAQGSGHT KSILNLRTNT
ETNNPCAKTI VKLFEVQKTG FNIQDMDIVA SEHLLHQSLV GKQSPFQNAY NVKGNATSAN
II
