ID   NCAP_NCMV               Reviewed;         431 AA.
AC   Q9JGU1;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   29-SEP-2021, entry version 59.
DE   RecName: Full=Nucleoprotein;
DE            Short=NP;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=Protein N;
GN   Name=N;
OS   Northern cereal mosaic virus (NCMV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Betarhabdovirinae;
OC   Cytorhabdovirus.
OX   NCBI_TaxID=1985704;
OH   NCBI_TaxID=4513; Hordeum vulgare (Barley).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=10963343; DOI=10.1007/s007050070096;
RA   Tanno F., Nakatsu A., Toriyama S., Kojima M.;
RT   "Complete nucleotide sequence of Northern cereal mosaic virus and its
RT   genome organization.";
RL   Arch. Virol. 145:1373-1384(2000).
CC   -!- FUNCTION: Encapsidates the genome, protecting it from nucleases. If
CC       expressed without protein P it binds non-specifically RNA and therefore
CC       can bind it's own mRNA. Interaction with protein P abolishes any non-
CC       specific RNA binding, and prevents phosphorylation. The soluble N-P
CC       complex encapsidates specifically the genomic RNA, with protein N
CC       protecting the genome like a pearl necklace. The encapsidated genomic
CC       RNA is termed the nucleocapsid (NC) and serves as template for viral
CC       transcription and replication. Protein N binds protein P in the NC
CC       through a different interaction, and can be phosphorylated. Subsequent
CC       viral replication is dependent on intracellular concentration of newly
CC       synthesized protein N. During replication, encapsidation by protein N
CC       is coupled to RNA synthesis and all replicative products are resistant
CC       to nucleases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
CC       genomic RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytorhabdovirus nucleocapsid protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB030277; BAA95344.1; -; Genomic_RNA.
DR   Proteomes; UP000007785; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004902; Rhabdo_ncap_2.
DR   Pfam; PF03216; Rhabdo_ncap_2; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Helical capsid protein; Host cytoplasm; Phosphoprotein;
KW   Reference proteome; Ribonucleoprotein; RNA-binding; Viral nucleoprotein;
KW   Virion.
FT   CHAIN           1..431
FT                   /note="Nucleoprotein"
FT                   /id="PRO_0000297613"
FT   REGION          412..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  48313 MW;  CA9377453AAA2D97 CRC64;
     MANEHKSPLD KRVTDLFKDI PTDISTHLIT GETFSNESFQ AIPVYTLTNV TVKQAVHLSY
     KLFESMKTTK CAAGYQYAIY LLAQRLLTPA AGSNDLVFKD YIPQGGSDLP QEIKNKIYVT
     TELSDSQTAG KSEAEKKKAT ADLIFGDNTD HDLQQVRSQD DETIIRFGSF ISAFLMKLIV
     KQQSNIVDGW NGMLERYTNF YGESPITAVP KPNADWLAGL KNYLISDPKI GHTWVRVISA
     AENALSVGDK SFQMVRYLAS LPLSLTGMHA YKLFLEVQKQ SNLGMQWLLE EMVSPKTLPA
     LEGIAKILKN FESRTSTRKP PYFRYARIMS PAYFQELQTK NCPELVYLLV CLLQKYEAFG
     AGQEPTKIVG IERVPANIRA EMSRAAGYIF SVAPQRNMGM YSDSMRKALV HQEKASTSRA
     GKEKADEVFG M