ID   NCAP_SVCV               Reviewed;         418 AA.
AC   Q91DS3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   23-FEB-2022, entry version 71.
DE   RecName: Full=Nucleoprotein;
DE            Short=NP;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=Protein N;
GN   Name=N;
OS   Spring viremia of carp virus (Rhabdovirus carpia).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Alpharhabdovirinae;
OC   Sprivivirus.
OX   NCBI_TaxID=696863;
OH   NCBI_TaxID=7962; Cyprinus carpio (Common carp).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Fijan reference;
RX   PubMed=11900842; DOI=10.1016/s0168-1702(01)00441-5;
RA   Hoffmann B., Schutze H., Mettenleiter T.C.;
RT   "Determination of the complete genomic sequence and analysis of the gene
RT   products of the virus of Spring Viremia of Carp, a fish rhabdovirus.";
RL   Virus Res. 84:89-100(2002).
CC   -!- FUNCTION: Encapsidates the genome, protecting it from nucleases. The
CC       encapsidated genomic RNA is termed the NC and serves as template for
CC       transcription and replication. Nucleocapsid assembly is concommitant
CC       with replication, therefore viral replication depends on the
CC       intracellular concentration of free N, termed N(0). All replicative
CC       products are resistant to nucleases. {ECO:0000250|UniProtKB:P03521}.
CC   -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
CC       genomic RNA. N in nucleocapsid binds the P protein and thereby
CC       positions the polymerase on the template. Interaction of N(0) with the
CC       P protein prevents the uncontrolled aggregation of N(0).
CC       {ECO:0000250|UniProtKB:P03521}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm. Note=The nucleocapsid is
CC       synthesized in the cytoplasm, and is subsequently transported via
CC       microtubules to the cell periphery. {ECO:0000250|UniProtKB:P03521}.
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DR   EMBL; AJ318079; CAC51333.1; -; Genomic_RNA.
DR   SMR; Q91DS3; -.
DR   Proteomes; UP000007541; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3570.10; -; 1.
DR   Gene3D; 1.10.3610.10; -; 1.
DR   InterPro; IPR000448; Rhabdo_ncapsid.
DR   InterPro; IPR023331; Rhabdovirus_ncapsid_C.
DR   InterPro; IPR023330; Rhabdovirus_ncapsid_N.
DR   InterPro; IPR035961; Rhabdovirus_nucleoprotein-like.
DR   Pfam; PF00945; Rhabdo_ncap; 1.
DR   SUPFAM; SSF140809; SSF140809; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Helical capsid protein; Host cytoplasm; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Viral nucleoprotein; Viral RNA replication;
KW   Virion.
FT   CHAIN           1..418
FT                   /note="Nucleoprotein"
FT                   /id="PRO_0000287267"
SQ   SEQUENCE   418 AA;  47046 MW;  493AB298D960BC50 CRC64;
     MSVIRIKTNA TVVAVLPASE DQADYPSTFF EGGNEIRLYV NKEEKLDVLR QYVYMGLVEK
     NCKIQHVNAY LYAVLKGERE LLEADWDSFG HKIGIRGEKI GPFNLVRVED IPDGLPDGKL
     NAEVSAEDDA WLPLFLLGLY RVGRASETAY RTLLMESLIK QCKAIKSDWV SPVTATHKYF
     DVWGNDGNYL KIVACVDMFY NHFKKSIKAT FRWGTIVSRF KDCAALATLG HVVKITGLTI
     EEVFTWVLQT EVAEELVKMM KPGQEIDNSS SYMPYLIDMG ISAKSPYSTI KNPSFHFWGQ
     LVAALCRSKR ALNARQPDEI DSMSISNASL LMAYALGSSP DIEQQFSTGD TYRKPPKEAS
     YLVSEEPKSR SVVEWIAWYS DVDNKPTDDM LMMAKRVAGT ISGPRDNSVG KWIKQTYG