ID   NCAP_TAVCV              Reviewed;         502 AA.
AC   Q5GA90;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Nucleoprotein;
DE            Short=NP;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=Protein N;
GN   Name=N;
OS   Taro vein chlorosis virus (TAVCV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Betarhabdovirinae;
OC   Alphanucleorhabdovirus.
OX   NCBI_TaxID=2749935;
OH   NCBI_TaxID=4460; Colocasia esculenta (Wild taro) (Arum esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=15659770; DOI=10.1099/vir.0.80591-0;
RA   Revill P., Trinh X., Dale J., Harding R.;
RT   "Taro vein chlorosis virus: characterization and variability of a new
RT   nucleorhabdovirus.";
RL   J. Gen. Virol. 86:491-499(2005).
CC   -!- FUNCTION: Encapsidates the genome, protecting it from nucleases. If
CC       expressed without protein P it binds non-specifically RNA and therefore
CC       can bind it's own mRNA. Interaction with protein P abolishes any non-
CC       specific RNA binding, and prevents phosphorylation. The soluble N-P
CC       complex encapsidates specifically the genomic RNA, with protein N
CC       protecting the genome like a pearl necklace. The encapsidated genomic
CC       RNA is termed the nucleocapsid (NC) and serves as template for viral
CC       transcription and replication. Protein N binds protein P in the NC
CC       through a different interaction, and can be phosphorylated. Subsequent
CC       viral replication is dependent on intracellular concentration of newly
CC       synthesized protein N. During replication, encapsidation by protein N
CC       is coupled to RNA synthesis and all replicative products are resistant
CC       to nucleases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
CC       genomic RNA (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nucleorhabdovirus nucleocapsid protein
CC       family. {ECO:0000305}.
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DR   EMBL; AY674964; AAV92082.1; -; Genomic_RNA.
DR   RefSeq; YP_224078.1; NC_006942.1.
DR   GeneID; 5076496; -.
DR   KEGG; vg:5076496; -.
DR   Proteomes; UP000007540; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004902; Rhabdo_ncap_2.
DR   Pfam; PF03216; Rhabdo_ncap_2; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Helical capsid protein; Host cytoplasm; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Superantigen; Viral nucleoprotein; Virion.
FT   CHAIN           1..502
FT                   /note="Nucleoprotein"
FT                   /id="PRO_0000299203"
FT   REGION          415..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   502 AA;  55399 MW;  B5B6A91E16D7ECD0 CRC64;
     MSYINIPDDV VSKYSDDLKT FTQKAGEIPS SKSLIPQTAY TIAALKTKLK FWEVTAKDDP
     TIASDWAGVC TAITAGTFSA TNLKTVCELA FNLRKPHETG NVFIHTVPSD WTSSISTDSV
     DTTPIPATES DATLSTVSAA VQSGAAEDAA TKAKAISFLC CALIRLSVKE PSHIMTAITS
     IRQRFGSLYG LASATLNAIT FTRQQLSRIK QGIETYSLAR GTIFYYVRYA DTTYGSSDKS
     YGVCRFLLFQ HLELEGMHIY KMILALLTEW STVPIGLLLT WIRNPKSALA VVEIKNIITN
     FDKAGVDKSW KYSRMIDNTF FLNISSRRNV YMCALLASLN KRHVPQGVGD YADPRNIAVI
     KAMDAAVKNQ VAIDVTLVER IYEKYLISAG STDAGTAYTL SRGTKRPNPA VFMSHQQAEG
     HPTKKRTWKS MVPPPPTLQL EDQQQRRLSP ELCEDCFSEL LRGKHHRILP PPVIPSSSSE
     VLFSKSRIME ISGGCSFDPI GF