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NCAP_THOGV
ID   NCAP_THOGV              Reviewed;         454 AA.
AC   P89216;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   02-JUN-2021, entry version 60.
DE   RecName: Full=Nucleoprotein;
DE   AltName: Full=Nucleocapsid protein;
DE            Short=Protein N;
GN   OrderedLocusNames=Segment 5;
OS   Thogoto virus (isolate SiAr 126) (Tho).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina;
OC   Insthoviricetes; Articulavirales; Orthomyxoviridae; Thogotovirus.
OX   NCBI_TaxID=126796;
OH   NCBI_TaxID=34610; Amblyomma variegatum (Tropical bont tick).
OH   NCBI_TaxID=10144; Cavia cutleri (Guinea pig).
OH   NCBI_TaxID=210652; Mungos mungo (Banded mongoose).
OH   NCBI_TaxID=34631; Rhipicephalus appendiculatus (Brown ear tick).
OH   NCBI_TaxID=6941; Rhipicephalus microplus (Cattle tick) (Boophilus microplus).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8970956; DOI=10.1128/jvi.70.12.8361-8367.1996;
RA   Weber F., Haller O., Kochs G.;
RT   "Nucleoprotein viral RNA and mRNA of Thogoto virus: a novel 'cap-stealing'
RT   mechanism in tick-borne orthomyxoviruses?";
RL   J. Virol. 70:8361-8367(1996).
CC   -!- FUNCTION: Encapsidates the negative strand viral RNA, protecting it
CC       from nucleases. The encapsidated genomic RNA is termed the
CC       ribonucleoprotein (RNP) and serves as template for transcription and
CC       replication. {ECO:0000250|UniProtKB:P03466}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the influenza viruses nucleoprotein family.
CC       {ECO:0000305}.
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DR   EMBL; X96872; CAA65616.1; -; Genomic_RNA.
DR   RefSeq; YP_145809.1; NC_006507.1.
DR   GeneID; 5075738; -.
DR   KEGG; vg:5075738; -.
DR   Proteomes; UP000008973; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0042025; C:host cell nucleus; IDA:UniProtKB.
DR   GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Capsid protein; Helical capsid protein; Reference proteome;
KW   Ribonucleoprotein; RNA-binding; Viral nucleoprotein;
KW   Viral penetration into host nucleus; Virion; Virus entry into host cell.
FT   CHAIN           1..454
FT                   /note="Nucleoprotein"
FT                   /id="PRO_0000079147"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   454 AA;  51850 MW;  E08A0EF537C13908 CRC64;
     MATDQMDISG PPPKKQHVDT ESQIPKMYEM IRDQMRTLAS THKIPLNIDH NCEVIGSIIM
     AACTNNRDLR PVDKYWFLMG PAGAEVMTEV EIDIQPQLQW AKGAVHDPKY KGQWYPFLAL
     LQISNKTKDT ILWQKYPVTQ ELEISNSLEI YANGHGIKDR LKNSRPRSVG PLVHLLHLKR
     LQENPPKNPK TKKPLESPAV NGIRKSIVGH LKRQCIGETQ KAMINQFEMG RWESLSTFAA
     SLLAIKPRIE NHFVLTYPLI ANCEDFAGAT LSDEWVFKAM EKISNKKTLR VCGPDEKWIS
     FMNQIYIHSV FQTTGEDLGV LEWVFGGRFC QRKEFGRYCK KSQTKVIGLF TFQYEYWSKP
     LKSAPRSIEG SKRGQISCRP SFKGKRPSYN NFTSIDALQS ASGSQTVSFY DQVREECQKY
     MDLKVEGTTC FYRKGGHVEV EFPGSAHCNT YLFG
 
 
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