NCDN_XENLA
ID NCDN_XENLA Reviewed; 720 AA.
AC Q640K1;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Neurochondrin;
GN Name=ncdn;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in signal transduction, in the nervous
CC system. Required for the spatial learning process. May also be involved
CC in neurite outgrowth (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:O35095}. Cell projection, dendrite
CC {ECO:0000250|UniProtKB:O35095}. Postsynapse
CC {ECO:0000250|UniProtKB:O35095}.
CC -!- SIMILARITY: Belongs to the neurochondrin family. {ECO:0000305}.
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DR EMBL; BC082624; AAH82624.1; -; mRNA.
DR RefSeq; NP_001087970.1; NM_001094501.1.
DR AlphaFoldDB; Q640K1; -.
DR SMR; Q640K1; -.
DR DNASU; 494655; -.
DR GeneID; 494655; -.
DR KEGG; xla:494655; -.
DR CTD; 494655; -.
DR Xenbase; XB-GENE-968623; ncdn.S.
DR OrthoDB; 311670at2759; -.
DR Proteomes; UP000186698; Chromosome 2S.
DR Bgee; 494655; Expressed in blastula and 19 other tissues.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR GO; GO:0030425; C:dendrite; ISS:UniProtKB.
DR GO; GO:0043025; C:neuronal cell body; ISS:UniProtKB.
DR GO; GO:0098794; C:postsynapse; IEA:UniProtKB-SubCell.
DR GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR InterPro; IPR008709; Neurochondrin.
DR PANTHER; PTHR13109; PTHR13109; 1.
DR Pfam; PF05536; Neurochondrin; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cytoplasm; Reference proteome; Synapse.
FT CHAIN 1..720
FT /note="Neurochondrin"
FT /id="PRO_0000324621"
SQ SEQUENCE 720 AA; 79957 MW; EB36545695E73859 CRC64;
MPNTTEEQSD EVNNLALEKC LKVLQEAQTD NEQFAALLLV TKCAQAQEIN NETRRRIFDA
VGFTFPNRLL FSNSVPEGCP QNLFKSLGIT LLACFSTDPV LAVHPQVVNK IPIFNETINI
SCQSGNKEVV SMVEDAYQCL LGILASPQGP KNLLSHGSIP YLCQAYMNRN HFWEKALQIL
TSLLTVLPPK CWKKSCTDLQ LLLTRLSEEF GKEEGEWKFQ LADLLPIFLP PSPILLETSW
GKQCLKQLCK GLLKILSNKL SISQRDPALK LAACLANSYG SSWIMAENKV VRSRFLALIV
NLACVEVRMA LEEPEPLTSR QSVITACYAL VEMGILACTK EEKHPVLGKE QKLQLIGVMQ
EACAAIIYYL QQVGWEKQED PFLLASVRLL GAWLAEETAC LKLEVIQLLP FLVHYMRTCH
QRSVICSKLP KEVSQVALLS NSWGNIWPGD AIRFLLPALC HLSAEEVPRK VLISEGVPAL
LCDYFQLQWD VLFAEDEPEG LQSAAELSLQ TCCGVFLNLV VTEPTFVGQE SCFVSLMKLL
MQSLPTLLTK EGHLVLVANF STLGLMMSRL LAENSVLHES NAEEFFKAAI HFLSHSHVPS
CQTDAGKPVI TLSESYSEAW EEISELWFLG VQAFSSCVHL LPWLSALVLR SSWLQDTLCL
LDNVSPKSVD SDLVTALQGM LTELAQSSSC CRDVIREKGG AEKANLYGMA ALEQCLAELS