ID   NCE1_SCHPO              Reviewed;          58 AA.
AC   C6Y4B6;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Non-classical export protein 1;
GN   Name=nce101; ORFNames=SPAC12G12.17;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=18488015; DOI=10.1038/nature07002;
RA   Wilhelm B.T., Marguerat S., Watt S., Schubert F., Wood V., Goodhead I.,
RA   Penkett C.J., Rogers J., Baehler J.;
RT   "Dynamic repertoire of a eukaryotic transcriptome surveyed at single-
RT   nucleotide resolution.";
RL   Nature 453:1239-1243(2008).
CC   -!- FUNCTION: Involved in a novel pathway of export of proteins that lack a
CC       cleavable signal sequence. May be part of the export machinery or may
CC       also be a substrate for non-classical export (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NCE101 family. {ECO:0000305}.
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DR   EMBL; CU329670; CBA11489.1; -; Genomic_DNA.
DR   RefSeq; XP_002742498.1; XM_002742452.2.
DR   AlphaFoldDB; C6Y4B6; -.
DR   SMR; C6Y4B6; -.
DR   PaxDb; C6Y4B6; -.
DR   EnsemblFungi; SPAC12G12.17.1; SPAC12G12.17.1:pep; SPAC12G12.17.
DR   PomBase; SPAC12G12.17; -.
DR   VEuPathDB; FungiDB:SPAC12G12.17; -.
DR   HOGENOM; CLU_188578_1_1_1; -.
DR   InParanoid; C6Y4B6; -.
DR   OMA; MQYPYLI; -.
DR   PRO; PR:C6Y4B6; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; ISO:PomBase.
DR   GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR   InterPro; IPR024242; NCE101.
DR   PANTHER; PTHR28011; PTHR28011; 1.
DR   Pfam; PF11654; NCE101; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..58
FT                   /note="Non-classical export protein 1"
FT                   /id="PRO_0000389167"
FT   TRANSMEM        10..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   58 AA;  6998 MW;  FB3920AA90717D16 CRC64;
     MSQPYLISKW MDPLFGIFVG TYGYYLYEKE HRPRGRSLRE LALRKWNKQA VSQQSMKN