ID   NCOA7_CHICK             Reviewed;         907 AA.
AC   Q5ZMS4;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Nuclear receptor coactivator 7;
GN   Name=NCOA7; ORFNames=RCJMB04_1f5;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Enhances the transcriptional activities of several nuclear
CC       receptors. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OXR1 family. {ECO:0000305}.
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DR   EMBL; AJ719310; CAG30969.1; -; mRNA.
DR   RefSeq; NP_001012896.1; NM_001012878.1.
DR   AlphaFoldDB; Q5ZMS4; -.
DR   SMR; Q5ZMS4; -.
DR   STRING; 9031.ENSGALP00000031109; -.
DR   PRIDE; Q5ZMS4; -.
DR   GeneID; 421717; -.
DR   KEGG; gga:421717; -.
DR   CTD; 135112; -.
DR   VEuPathDB; HostDB:geneid_421717; -.
DR   eggNOG; KOG2372; Eukaryota.
DR   InParanoid; Q5ZMS4; -.
DR   OrthoDB; 767847at2759; -.
DR   PhylomeDB; Q5ZMS4; -.
DR   PRO; PR:Q5ZMS4; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030374; F:nuclear receptor coactivator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   CDD; cd00118; LysM; 1.
DR   Gene3D; 3.10.350.10; -; 1.
DR   InterPro; IPR018392; LysM_dom.
DR   InterPro; IPR036779; LysM_dom_sf.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF01476; LysM; 1.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00257; LysM; 1.
DR   SMART; SM00584; TLDc; 1.
DR   SUPFAM; SSF54106; SSF54106; 1.
DR   PROSITE; PS51782; LYSM; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   2: Evidence at transcript level;
KW   Activator; Coiled coil; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..907
FT                   /note="Nuclear receptor coactivator 7"
FT                   /id="PRO_0000245231"
FT   DOMAIN          125..168
FT                   /note="LysM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT   DOMAIN          746..907
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          63..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          99..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          335..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          401..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1..29
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        27..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..120
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   907 AA;  102062 MW;  F0253ECA62A13E43 CRC64;
     METKEEKKER RQGYFARLKK KRQAKQNTET VSANSPGSPV SKTPAEKDDE SKVILEQISS
     SGDNCKFAGE KETVPEKEKR KKKYNQLKDI RRTELKRYYS TDDNQNKTNE KKEKKMVSQK
     PHGTIEYTAG NQDTINSIAL KFNITPNKLV ELNKLFTHTI VPGQILFVPE TSVARLPSFS
     PGAPISPSSS DAEYDKLPDA DLARKAFKPV ERVLSSTSEE DEPVVVKFLK MNCRYFTDGK
     GVVGGVMIVT PNNIMFDPHK SDPLVIENGC EEYGLICPME EVVSIALYND ISHMKIKDAL
     PSDIPKDLCP LYRPGEWEDL SSEKDINPFS KFKSLSKEKR QQNGDSPNVP GAKQINPSDK
     EKSADFEVLQ SSESTGSIKS KSLEFYNNIT ATEHLEKFAA DPHVKEPSEE KNVSDIRTKE
     DSLSGGGDDF IDLEKVPSPM DRGLDRKISL MEGLLADPRE LGRTKQQVTK PTTEVQEHFT
     VDSLEKKDSV EPKADLDLEL CEKQDVIPEV NKCVSSPTGK VETALDTKKE LEKDKLIEFY
     LNKDGSGSQS SEDLHKAEIQ KGENNKAIGI DLTLSCSKSQ ADEVHTVKSM ELDSCCVGRK
     AASLESSAAA AEEKDLKESL DSSLVPAVDK TCQETQLDNQ SEVRLWLLQK IQVPIEDMLP
     SKEEKSKTPP MFLCIKVGKP MRKSFVSQST TVSQQYSKKI KQPEYWFAVP REIITVEEAK
     RRKSVCSYYG EEDDDDALPV LKHHSALLEN MHIEQLARRL PARVQGYPWR LAYSTLEHGT
     SLKTLYRKSA SLDSPVLLVI KDMDNQIFGA YATHPFRFSD HYYGTGETFL YTFSPNFKVF
     KWSGENTYFI NGDMTSLELG GGGGRFGLWL DADLYHGRSN SCSTFNNDIL SKKEDFIIQD
     VEVWTFE