ID   NDB2S_MESMA             Reviewed;          74 AA.
AC   Q8N0N8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Peptide BmKa2 {ECO:0000303|PubMed:15062994};
DE   AltName: Full=Acidic venom peptide Ka2 {ECO:0000303|PubMed:15062994};
DE   AltName: Full=Non-disulfide-bridged peptide 6.2 {ECO:0000303|PubMed:16036557};
DE            Short=NDBP-6.2 {ECO:0000303|PubMed:16036557};
DE   Flags: Precursor;
OS   Mesobuthus martensii (Manchurian scorpion) (Buthus martensii).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Mesobuthus.
OX   NCBI_TaxID=34649;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=15062994; DOI=10.1016/j.peptides.2003.12.003;
RA   Zeng X.-C., Wang S.-X., Zhu Y., Zhu S.-Y., Li W.-X.;
RT   "Identification and functional characterization of novel scorpion venom
RT   peptides with no disulfide bridge from Buthus martensii Karsch.";
RL   Peptides 25:143-150(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16040157; DOI=10.1016/j.peptides.2005.06.008;
RA   Luo F., Zeng X.-C., Hahin R., Cao Z.-J., Liu H., Li W.-X.;
RT   "Genomic organization of four novel nondisulfide-bridged peptides from
RT   scorpion Mesobuthus martensii Karsch: gaining insight into evolutionary
RT   mechanism.";
RL   Peptides 26:2427-2433(2005).
RN   [3]
RP   NOMENCLATURE.
RX   PubMed=16036557; DOI=10.1080/15216540500058899;
RA   Zeng X.C., Corzo G., Hahin R.;
RT   "Scorpion venom peptides without disulfide bridges.";
RL   IUBMB Life 57:13-21(2005).
CC   -!- FUNCTION: Highly acidic peptide that may have antibacterial activity.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the non-disulfide-bridged peptide (NDBP)
CC       superfamily. Long chain multifunctional peptide (group 2) family.
CC       {ECO:0000305}.
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DR   EMBL; AF150012; AAM33226.1; -; mRNA.
DR   EMBL; AY648240; AAV64159.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8N0N8; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..74
FT                   /note="Peptide BmKa2"
FT                   /id="PRO_0000231495"
SQ   SEQUENCE   74 AA;  8396 MW;  86129002FE4ACE9E CRC64;
     MSSKTLLVLL LVGVLVSTFF TADAYPASMD NYDDALEELD NLDLDDYFDL EPADFVLLDM
     WANMLESSDF DDME