NDB4T_TITCO
ID NDB4T_TITCO Reviewed; 73 AA.
AC Q5G8B4;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 24.
DE RecName: Full=Putative antimicrobial peptide clone 5;
DE Flags: Precursor;
OS Tityus costatus (Brazilian scorpion).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC Scorpiones; Buthida; Buthoidea; Buthidae; Tityus.
OX NCBI_TaxID=309814;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=15683865; DOI=10.1016/j.toxicon.2004.10.014;
RA Diego-Garcia E., Batista C.V.F., Garcia-Gomez B.I., Lucas S., Candido D.M.,
RA Gomez-Lagunas F., Possani L.D.;
RT "The Brazilian scorpion Tityus costatus Karsch: genes, peptides and
RT function.";
RL Toxicon 45:273-283(2005).
CC -!- FUNCTION: Antibacterial peptide. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the non-disulfide-bridged peptide (NDBP)
CC superfamily. Short antimicrobial peptide (group 4) family.
CC {ECO:0000305}.
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DR EMBL; AY740687; AAW72457.1; -; mRNA.
DR AlphaFoldDB; Q5G8B4; -.
DR SMR; Q5G8B4; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antibiotic; Antimicrobial; Cleavage on pair of basic residues; Secreted;
KW Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT PEPTIDE 23..39
FT /note="Putative antimicrobial peptide clone 5"
FT /id="PRO_0000231511"
FT PROPEP 45..73
FT /id="PRO_0000231512"
SQ SEQUENCE 73 AA; 8485 MW; E6DB77E1B904E749 CRC64;
MQIKHLITLF FLVLIGADQC SAFFSLIPSL IGGLVFAIKG RKKREVSPQI DQYRNFQKRE
AELEELLDRL PMY