ID   NDB4W_CHATY             Reviewed;          17 AA.
AC   P0DME5;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Peptide Ctry2801 {ECO:0000303|PubMed:22791717};
OS   Chaerilus tryznai (Scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Chaerilida; Chaeriloidea; Chaerilidae; Chaerilus.
OX   NCBI_TaxID=1464547;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND SYNTHESIS.
RC   TISSUE=Venom gland;
RX   PubMed=22791717; DOI=10.1074/jbc.m112.370312;
RA   Zhao Z., Hong W., Zeng Z., Wu Y., Hu K., Tian X., Li W., Cao Z.;
RT   "Mucroporin-M1 inhibits hepatitis B virus replication by activating the
RT   mitogen-activated protein kinase (MAPK) pathway and down-regulating
RT   HNF4alpha in vitro and in vivo.";
RL   J. Biol. Chem. 287:30181-30190(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Inhibits hepatitis B virus replication in the HepG2.2.15
CC       cell line by about 40%. {ECO:0000305|PubMed:22791717}.
CC   -!- SIMILARITY: Belongs to the non-disulfide-bridged peptide (NDBP)
CC       superfamily. Short antimicrobial peptide (group 4) family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P0DME5; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Amidation; Antimicrobial; Antiviral protein; Secreted.
FT   PEPTIDE         1..17
FT                   /note="Peptide Ctry2801"
FT                   /id="PRO_0000428683"
FT   MOD_RES         17
FT                   /note="Lysine amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   17 AA;  1748 MW;  AE03B5EBF7A36744 CRC64;
     FLSLIPGAIS AIASLFK