ID   NDB4X_CHATC             Reviewed;          69 AA.
AC   P0DMF7;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Peptide Ctri9594 {ECO:0000303|PubMed:23415044};
DE   Flags: Precursor;
OS   Chaerilus tricostatus (Scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Chaerilida; Chaeriloidea; Chaerilidae; Chaerilus.
OX   NCBI_TaxID=1055734;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND SYNTHESIS OF 24-35.
RC   TISSUE=Venom gland;
RX   PubMed=23415044; DOI=10.1016/j.biomaterials.2013.01.075;
RA   Hong W., Zhang R., Di Z., He Y., Zhao Z., Hu J., Wu Y., Li W., Cao Z.;
RT   "Design of histidine-rich peptides with enhanced bioavailability and
RT   inhibitory activity against hepatitis C virus.";
RL   Biomaterials 34:3511-3522(2013).
CC   -!- FUNCTION: Antimicrobial peptide. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Shows a low ability to inhibit hepatitis C virus (HCV)
CC       infection in Huh7.5.1 cells. {ECO:0000305|PubMed:23415044}.
CC   -!- SIMILARITY: Belongs to the non-disulfide-bridged peptide (NDBP)
CC       superfamily. Short antimicrobial peptide (group 4) family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P0DMF7; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Antiviral protein; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   PEPTIDE         22..35
FT                   /note="Peptide Ctri9594"
FT                   /id="PRO_0000428705"
FT   PROPEP          36..69
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000428706"
SQ   SEQUENCE   69 AA;  7934 MW;  3DEAA9C55BEB6A20 CRC64;
     MKTQTALFFF FLFSLMVATQ SGVVDTLKNL LMGLLSKRAL RNQNFVEYAY DPSLSAADWR
     ALDTLFENY