ID   NDD_BPK3                Reviewed;         152 AA.
AC   P69191; P42266;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   12-AUG-2020, entry version 22.
DE   RecName: Full=Nucleoid disruption protein;
DE   AltName: Full=Nuclear disruption protein;
GN   Name=ndd;
OS   Enterobacteria phage K3 (Bacteriophage K3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus;
OC   unclassified Tequatrovirus.
OX   NCBI_TaxID=10674;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8163181; DOI=10.1016/0378-1119(94)90121-x;
RA   Bouet J.-Y., Woszczyk J., Repoila F., Francois V., Louarn J.-M.,
RA   Krisch H.M.;
RT   "Direct PCR sequencing of the ndd gene of bacteriophage T4: identification
RT   of a product involved in bacterial nucleoid disruption.";
RL   Gene 141:9-16(1994).
CC   -!- FUNCTION: Disorganizes the host nucleoid and inhibits replication, but
CC       without host DNA cleavage or degradation. Only the architecture of the
CC       nucleoid is affected. May act on the host chromosomal sequences that
CC       determine the structure of the nucleoid. Binds to dsDNA but not to
CC       ssDNA. {ECO:0000250|UniProtKB:P15556}.
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DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0098673; P:inhibition of host DNA replication by virus; IEA:UniProtKB-KW.
DR   GO; GO:0060153; P:modulation by virus of host cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR009514; Phage_Ndd.
DR   Pfam; PF06591; Phage_T4_Ndd; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host-virus interaction;
KW   Inhibition of host DNA replication by virus;
KW   Modulation of host cell cycle by virus.
FT   CHAIN           1..152
FT                   /note="Nucleoid disruption protein"
FT                   /id="PRO_0000164962"
SQ   SEQUENCE   152 AA;  17147 MW;  E03886AFF94DA5B4 CRC64;
     MKYMTVTDLN NAGATVIGTI KGGEWFLGTP HKDILSKPGF YFLVSKLDGR PFSNPCVSAR
     FYVGNQRSKQ GFSAVLSHIR QRRSQLARTI ANNNVPYTVF YLPASKMKPL TTGFGKGQLA
     LAFTRNHHSE YQTLEEMNRM LADNFKFVLQ AY