NDE1_ASPFU
ID NDE1_ASPFU Reviewed; 621 AA.
AC Q4X1V0;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Nuclear distribution protein nudE homolog 1;
GN Name=nde1; ORFNames=AFUA_2G08690;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- FUNCTION: Required for nuclear migration within hyphae during
CC vegetative growth. {ECO:0000250}.
CC -!- SUBUNIT: Self-associates. Interacts with nudF (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Note=Localizes to the
CC plus ends of microtubules. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the nudE family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAHF01000001; EAL93165.1; -; Genomic_DNA.
DR RefSeq; XP_755203.1; XM_750110.1.
DR AlphaFoldDB; Q4X1V0; -.
DR SMR; Q4X1V0; -.
DR STRING; 746128.CADAFUBP00002404; -.
DR PRIDE; Q4X1V0; -.
DR EnsemblFungi; EAL93165; EAL93165; AFUA_2G08690.
DR GeneID; 3513634; -.
DR KEGG; afm:AFUA_2G08690; -.
DR VEuPathDB; FungiDB:Afu2g08690; -.
DR eggNOG; KOG1853; Eukaryota.
DR HOGENOM; CLU_034391_0_0_1; -.
DR InParanoid; Q4X1V0; -.
DR OMA; WKTKYKQ; -.
DR OrthoDB; 801243at2759; -.
DR Proteomes; UP000002530; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR GO; GO:0051642; P:centrosome localization; IBA:GO_Central.
DR GO; GO:0007059; P:chromosome segregation; IBA:GO_Central.
DR GO; GO:0051303; P:establishment of chromosome localization; IBA:GO_Central.
DR GO; GO:0000132; P:establishment of mitotic spindle orientation; IBA:GO_Central.
DR GO; GO:0007020; P:microtubule nucleation; IBA:GO_Central.
DR GO; GO:0047496; P:vesicle transport along microtubule; IBA:GO_Central.
DR InterPro; IPR033494; NUDE.
DR InterPro; IPR006964; NUDE_dom.
DR PANTHER; PTHR10921; PTHR10921; 1.
DR Pfam; PF04880; NUDE_C; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome;
KW Transport.
FT CHAIN 1..621
FT /note="Nuclear distribution protein nudE homolog 1"
FT /id="PRO_0000240222"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 569..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 18..219
FT /evidence="ECO:0000255"
FT COMPBIAS 226..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 621 AA; 68763 MW; 97556A14F64D164F CRC64;
MPSADGSSSA RPNGTSSRSD QLAWYKSQYE QLEAELADFQ ASSRELEAEL EKDIEASEKR
ERLLKEKVDS LKYEVEEWKV RLEFTTFIAD DGPRANLSLP RQTKYKQSKA EGNSAQNTLQ
KEITTLRDAN RTLQLKLRDI EVANDDYERQ ARHTTSSLED LESKYNVAIE RAVLLEEEMR
AGEQEREKLR IENQRLRDEL SDLKIETEII HEKLRNAELQ NSRRRKPISL RSPSTPQTPD
LFNRSPASSI VSSPLFSTPT LKTSLMSATA TPPSPPISES SSSLRKSMNA MPGFPLQKAS
ASDSSFGSRS LHGSRTQKHN NHSRATSYAF TSNRPTPSVT NRPGLPKPKP KPNENTNKHN
NNARSSGLPK SGSLYQIRGL IGKMQKLEER VQSAKSKLPP PSDSPSRTSS RSGSILGESP
VASTITARRN SRKRLSGSSF SSSVRDGDSV PSYAPHSRPS FGARTQGDSR PSSRTSYSSH
SSVSHSTHPS VTPSTRPESR QSRTKTPLGH YSTNPTTESR RPRSSLSNPS NQNGVVNGMA
HIDEDEDLAM HMSLRARISE IRETRLPSIS TPTGLKKRTP SGISGIPAPR TLRTSTGFDR
LEGDMGPPER KSNITDLGET Y
