NDE1_USTMA
ID NDE1_USTMA Reviewed; 635 AA.
AC Q4P0N6; A0A0D1E347;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-SEP-2015, sequence version 2.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Nuclear distribution protein nudE homolog 1;
GN Name=NDE1; ORFNames=UMAG_12335;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for nuclear migration. {ECO:0000250}.
CC -!- SUBUNIT: Self-associates. Interacts with PAC1 (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Note=Localizes to the
CC plus ends of microtubules. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the nudE family. {ECO:0000305}.
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DR EMBL; CM003143; KIS70241.1; -; Genomic_DNA.
DR RefSeq; XP_011388417.1; XM_011390115.1.
DR AlphaFoldDB; Q4P0N6; -.
DR SMR; Q4P0N6; -.
DR STRING; 5270.UM06327P0; -.
DR EnsemblFungi; KIS70241; KIS70241; UMAG_12335.
DR GeneID; 23568080; -.
DR KEGG; uma:UMAG_12335; -.
DR VEuPathDB; FungiDB:UMAG_12335; -.
DR eggNOG; KOG1853; Eukaryota.
DR HOGENOM; CLU_028360_0_0_1; -.
DR InParanoid; Q4P0N6; -.
DR OrthoDB; 858880at2759; -.
DR Proteomes; UP000000561; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR GO; GO:0051642; P:centrosome localization; IBA:GO_Central.
DR GO; GO:0007059; P:chromosome segregation; IBA:GO_Central.
DR GO; GO:0051303; P:establishment of chromosome localization; IBA:GO_Central.
DR GO; GO:0000132; P:establishment of mitotic spindle orientation; IBA:GO_Central.
DR GO; GO:0007020; P:microtubule nucleation; IBA:GO_Central.
DR GO; GO:0047496; P:vesicle transport along microtubule; IBA:GO_Central.
DR InterPro; IPR033494; NUDE.
DR InterPro; IPR006964; NUDE_dom.
DR PANTHER; PTHR10921; PTHR10921; 1.
DR Pfam; PF04880; NUDE_C; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome;
KW Transport.
FT CHAIN 1..635
FT /note="Nuclear distribution protein nudE homolog 1"
FT /id="PRO_0000240227"
FT REGION 35..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 14..192
FT /evidence="ECO:0000255"
FT COMPBIAS 39..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 68418 MW; 0EE28DE3D958182D CRC64;
MSEHGADLRF DSPEKEIKHW KSKVADMQDA LRETESSLQD FVESSKELEQ EMEKELSASN
KTISDLKRRN EQLSGDLEDW KSKYSRALSE HNATLTTLQK ELGQLRESVD IYKAKLRDTE
LTNDELENAE RMVASSLADM EGKYNKTIEK TALLEEELIE KTRLDEENQR LKDELREMTE
EMTILRDLVT RSRAISRADT MASSTYDDST APRSEQSFDS SPIKPSSAAR ATERPSSRQA
LSSPVTNRVP ISRRLGAMGH NRRLSRDVRA AEAPSLAAVL DDSPTATTTS AAPTRSSTLS
RRDPLAATPY HHGASTSHGL TSSPSARAQL RASVRAAARI GGAVSVSSAP RSTNLSANGG
AAGSKRMMAE MISKMKALES RINSAKDLSR VVGPGDESAI PRPSSRMATI GSPSANGHNS
IHMPTSTPRA PRASMDGNRT IGSSIPVPSR VRRPSSRMSE RGTPPMPSLG LPRAQTPSSL
HARGSSRADG PSPLPLHEFM DHDPASTLPH AARYAAAQAS VAKRRTSMSG SGMSHSASHG
SLAKVRSGST LPRSTTPSTV AAPRVTQSSM TYYGAEASMS KRTPLSTRLA SSHRNASSAR
GSINGPPSSW KTSAMPAQTL SRSRSSSLGS ETETF
