NDF5_ARATH
ID NDF5_ARATH Reviewed; 354 AA.
AC Q9C503; B9DFW7; Q0WU84; Q8LBH1;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Protein NDH-DEPENDENT CYCLIC ELECTRON FLOW 5 {ECO:0000305};
DE Flags: Precursor;
GN Name=NDF5 {ECO:0000303|PubMed:19122188};
GN OrderedLocusNames=At1g55370 {ECO:0000312|Araport:AT1G55370};
GN ORFNames=F7A10.12 {ECO:0000312|EMBL:AAG51558.1},
GN T18I3.2 {ECO:0000312|EMBL:AAG50849.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-354 (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=19122188; DOI=10.1093/pcp/pcn205;
RA Ishida S., Takabayashi A., Ishikawa N., Hano Y., Endo T., Sato F.;
RT "A novel nuclear-encoded protein, NDH-dependent cyclic electron flow 5, is
RT essential for the accumulation of chloroplast NAD(P)H dehydrogenase
RT complexes.";
RL Plant Cell Physiol. 50:383-393(2009).
CC -!- FUNCTION: Required for both formation and activity of the chloroplast
CC NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron
CC transport chain. May function in assembly or stabilization of the NDH
CC complex. {ECO:0000269|PubMed:19122188}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000269|PubMed:19122188}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9C503-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9C503-2; Sequence=VSP_057692, VSP_057693;
CC -!- DISRUPTION PHENOTYPE: Impaired chloroplastic NAD(P)H dehydrogenase
CC (NDH) activity, probably due to a reduced stability of the NDH complex.
CC {ECO:0000269|PubMed:19122188}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC027034; AAG51558.1; -; Genomic_DNA.
DR EMBL; AC079287; AAG50849.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33239.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33240.1; -; Genomic_DNA.
DR EMBL; AK227298; BAE99314.1; -; mRNA.
DR EMBL; AY087212; AAM64767.1; -; mRNA.
DR EMBL; AK316929; BAH19634.1; -; mRNA.
DR PIR; A96596; A96596.
DR RefSeq; NP_564687.1; NM_104413.4. [Q9C503-1]
DR RefSeq; NP_849810.1; NM_179479.3. [Q9C503-2]
DR AlphaFoldDB; Q9C503; -.
DR SMR; Q9C503; -.
DR STRING; 3702.AT1G55370.2; -.
DR PaxDb; Q9C503; -.
DR PRIDE; Q9C503; -.
DR ProteomicsDB; 251289; -. [Q9C503-1]
DR EnsemblPlants; AT1G55370.1; AT1G55370.1; AT1G55370. [Q9C503-2]
DR EnsemblPlants; AT1G55370.2; AT1G55370.2; AT1G55370. [Q9C503-1]
DR GeneID; 841984; -.
DR Gramene; AT1G55370.1; AT1G55370.1; AT1G55370. [Q9C503-2]
DR Gramene; AT1G55370.2; AT1G55370.2; AT1G55370. [Q9C503-1]
DR KEGG; ath:AT1G55370; -.
DR Araport; AT1G55370; -.
DR TAIR; locus:2035646; AT1G55370.
DR eggNOG; ENOG502QS85; Eukaryota.
DR HOGENOM; CLU_048345_0_0_1; -.
DR InParanoid; Q9C503; -.
DR OMA; IFSSWGT; -.
DR PhylomeDB; Q9C503; -.
DR PRO; PR:Q9C503; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C503; baseline and differential.
DR Genevisible; Q9C503; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IDA:TAIR.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0047938; F:glucose-6-phosphate 1-epimerase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0009773; P:photosynthetic electron transport in photosystem I; IMP:TAIR.
DR GO; GO:0010628; P:positive regulation of gene expression; IMP:TAIR.
DR Gene3D; 2.70.98.10; -; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR SUPFAM; SSF74650; SSF74650; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Chaperone; Chloroplast; Membrane; Plastid;
KW Reference proteome; Thylakoid; Transit peptide.
FT TRANSIT 1..49
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 50..354
FT /note="Protein NDH-DEPENDENT CYCLIC ELECTRON FLOW 5"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433245"
FT VAR_SEQ 291..308
FT /note="GRRNSVVVGREGFEEVYM -> VVILTKLQLYLNFLCGFI (in isoform
FT 2)"
FT /id="VSP_057692"
FT VAR_SEQ 309..354
FT /note="Missing (in isoform 2)"
FT /id="VSP_057693"
FT CONFLICT 91
FT /note="N -> D (in Ref. 4; AAM64767)"
FT /evidence="ECO:0000305"
FT CONFLICT 311
FT /note="P -> S (in Ref. 4; AAM64767)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 354 AA; 39316 MW; DF61367D40EF764A CRC64;
MALVHYMNVS RSTFPLSRSS KINLSSSFAS LPLQFHKNIK RLESSVPPSA SASASPAFPI
DVEYLRREFS GHGATFEDIG ETCIARLKLD NGSSANVMLT RGMITSYKVR VWHGGKVELL
HTWVEQEEEE VVIRGGVSSA FRSSDSDEIS DWRLQGISGD SKDCVQMELR RSDKKIKEIE
LKQIISLREN TLSIELSMTN KGISPIKLEG CSLVSYLTVS TPEATYAVGL EGSDFVETTP
FLPRFGVVQG EKEEEKPGFG GEEESNYKQL NREMSRIYTC APKSFTVIDR GRRNSVVVGR
EGFEEVYMYS PGSRLESYTK SAYVCIGPSS LLSPISLESG CVWRGVLHLH NPNS
