ID   NDHH_PAUCH              Reviewed;         406 AA.
AC   B1X4A5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=NAD(P)H-quinone oxidoreductase subunit H, organellar chromatophore {ECO:0000255|HAMAP-Rule:MF_01358};
DE            EC=7.1.1.- {ECO:0000255|HAMAP-Rule:MF_01358};
DE   AltName: Full=NAD(P)H dehydrogenase subunit H;
DE   AltName: Full=NADH-plastoquinone oxidoreductase 49 kDa subunit {ECO:0000255|HAMAP-Rule:MF_01358};
DE   AltName: Full=NADH-plastoquinone oxidoreductase subunit H {ECO:0000255|HAMAP-Rule:MF_01358};
GN   Name=ndhH {ECO:0000255|HAMAP-Rule:MF_01358}; OrderedLocusNames=PCC_0333;
OS   Paulinella chromatophora.
OG   Plastid; Organellar chromatophore.
OC   Eukaryota; Sar; Rhizaria; Imbricatea; Silicofilosea; Euglyphida;
OC   Paulinellidae; Paulinella.
OX   NCBI_TaxID=39717;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18356055; DOI=10.1016/j.cub.2008.02.051;
RA   Nowack E.C.M., Melkonian M., Gloeckner G.;
RT   "Chromatophore genome sequence of Paulinella sheds light on acquisition of
RT   photosynthesis by eukaryotes.";
RL   Curr. Biol. 18:410-418(2008).
CC   -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN
CC       and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain
CC       and possibly in a chloroplast respiratory chain. The immediate electron
CC       acceptor for the enzyme in this species is believed to be
CC       plastoquinone. Couples the redox reaction to proton translocation, and
CC       thus conserves the redox energy in a proton gradient.
CC       {ECO:0000255|HAMAP-Rule:MF_01358}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC         Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01358};
CC   -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of which
CC       are encoded in the nucleus. {ECO:0000255|HAMAP-Rule:MF_01358}.
CC   -!- SUBCELLULAR LOCATION: Plastid, organellar chromatophore thylakoid
CC       membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01358}; Stromal side {ECO:0000255|HAMAP-Rule:MF_01358}.
CC   -!- SIMILARITY: Belongs to the complex I 49 kDa subunit family.
CC       {ECO:0000255|HAMAP-Rule:MF_01358}.
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DR   EMBL; CP000815; ACB42774.1; -; Genomic_DNA.
DR   RefSeq; YP_002048984.1; NC_011087.1.
DR   AlphaFoldDB; B1X4A5; -.
DR   SMR; B1X4A5; -.
DR   PRIDE; B1X4A5; -.
DR   GeneID; 6481295; -.
DR   GO; GO:0070118; C:organellar chromatophore thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0009536; C:plastid; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050136; F:NADH dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.645.10; -; 1.
DR   HAMAP; MF_01358; NDH1_NuoD; 1.
DR   InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR   InterPro; IPR014029; NADH_UbQ_OxRdtase_49kDa_CS.
DR   InterPro; IPR022885; NDH1_su_D/H.
DR   InterPro; IPR029014; NiFe-Hase_large.
DR   PANTHER; PTHR11993; PTHR11993; 1.
DR   Pfam; PF00346; Complex1_49kDa; 1.
DR   SUPFAM; SSF56762; SSF56762; 1.
DR   TIGRFAMs; TIGR01962; NuoD; 1.
DR   PROSITE; PS00535; COMPLEX1_49K; 1.
PE   3: Inferred from homology;
KW   Membrane; NAD; NADP; Organellar chromatophore; Plastid; Plastoquinone;
KW   Quinone; Thylakoid; Translocase; Transport.
FT   CHAIN           1..406
FT                   /note="NAD(P)H-quinone oxidoreductase subunit H, organellar
FT                   chromatophore"
FT                   /id="PRO_0000371959"
SQ   SEQUENCE   406 AA;  46300 MW;  6350C68E830E9C4E CRC64;
     MTQLETRTEP MIINFGPHHP SMHGVLRLVV TLDGEDVVDC EPVIGYLHRG MEKIAESRTA
     ITFVPYVSRW DYAAGMFNEA ITVNATEKLM DLEIPRRASY IRVLMLELNR IANHLLWLGP
     FLADVGAQTP FFYIFREREM IYDLWEAVTG QRLINNNYFR VGGVACDLPF GWLDKCEDFC
     DWFGPKIDEY EQLITNNPIF RRRIEGLGVI SREQAINWSL SGPMLRASGV PWDLRKVDHY
     ECYDDFDWDI AWAKEGDCYA RYLVRIEEMR QSLRILKQAL KMIPGGPTEN LEAQCGFDST
     DTNQDLDKKR SVATGEVSGN EYTIGPKKIN LNKCPEGELY CRVESGKGEL GVFIISNGEA
     NPWRWKIRAA DFNNLQILPH ILTGAKVADV MAILGSIDVI MGSVDR