NDHM_VITVI
ID NDHM_VITVI Reviewed; 208 AA.
AC A7NVJ4; E0CR06;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit M, chloroplastic {ECO:0000305};
DE EC=7.1.1.- {ECO:0000305};
DE AltName: Full=NAD(P)H dehydrogenase subunit M {ECO:0000305};
DE Short=NDH subunit M {ECO:0000305};
DE Short=NDH-M {ECO:0000250|UniProtKB:Q2V2S7};
DE AltName: Full=NADH-plastoquinone oxidoreductase subunit M {ECO:0000305};
DE Flags: Precursor;
GN Name=ndhM {ECO:0000305}; Synonyms=NDH-M {ECO:0000250|UniProtKB:Q2V2S7};
GN OrderedLocusNames=VIT_18s0001g01660;
GN ORFNames=GSVIVT00015457001, LOC100264425;
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Cabernet Sauvignon;
RA Goes da Silva F., Lim H., Iandolino A., Baek J., Jones K., Walker M.A.,
RA Cook D.R.;
RT "Transcriptional responses of Vitis vinifera to infection by the bacterial
RT pathogen Xylella fastidiosa.";
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024;
RX PubMed=17721507; DOI=10.1038/nature06148;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN
CC and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain
CC and possibly in a chloroplast respiratory chain. The immediate electron
CC acceptor for the enzyme in this species is believed to be
CC plastoquinone. Couples the redox reaction to proton translocation, and
CC thus conserves the redox energy in a proton gradient. {ECO:0000305}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC Evidence={ECO:0000305};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC Evidence={ECO:0000305};
CC -!- SUBUNIT: Part of the chloroplast NDH complex, composed of a mixture of
CC chloroplast and nucleus encoded subunits. Component of the NDH
CC subcomplex A, at least composed of ndhH, ndhI, ndhJ, ndhK, ndhL, ndhM,
CC ndhN and ndhO. {ECO:0000250|UniProtKB:Q2V2S7}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000250|UniProtKB:Q9CAC5}; Peripheral membrane protein
CC {ECO:0000305}; Stromal side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NDH complex subunit M family. {ECO:0000305}.
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DR EMBL; CA815794; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; FN595227; CBI18960.3; -; Genomic_DNA.
DR RefSeq; XP_002285884.1; XM_002285848.3.
DR AlphaFoldDB; A7NVJ4; -.
DR SMR; A7NVJ4; -.
DR STRING; 29760.VIT_18s0001g01660.t01; -.
DR EnsemblPlants; Vitvi18g00216_t001; Vitvi18g00216_P001; Vitvi18g00216.
DR GeneID; 100264425; -.
DR Gramene; Vitvi18g00216_t001; Vitvi18g00216_P001; Vitvi18g00216.
DR KEGG; vvi:100264425; -.
DR eggNOG; ENOG502QUN1; Eukaryota.
DR HOGENOM; CLU_089187_0_0_1; -.
DR InParanoid; A7NVJ4; -.
DR OMA; GQMEDVN; -.
DR OrthoDB; 1404408at2759; -.
DR Proteomes; UP000009183; Chromosome 18.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR InterPro; IPR018922; NdhM.
DR PANTHER; PTHR36900; PTHR36900; 1.
DR Pfam; PF10664; NdhM; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; NAD; NADP; Plastid; Plastoquinone; Quinone;
KW Reference proteome; Thylakoid; Transit peptide; Translocase; Transport.
FT TRANSIT 1..21
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 22..208
FT /note="NAD(P)H-quinone oxidoreductase subunit M,
FT chloroplastic"
FT /id="PRO_0000352665"
FT REGION 37..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 109
FT /note="E -> G (in Ref. 1; CA815794)"
FT /evidence="ECO:0000305"
FT CONFLICT 202
FT /note="G -> D (in Ref. 1; CA815794)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 208 AA; 24167 MW; 15D7927A3D657570 CRC64;
MAATSSYTAC TKFSMLGWIG GKRELRKRRA FFISAQQQAE VEESQQVNAQ EEEQEKMKQQ
GKQKLPRPVE PQVNVKSKNM SREYGGQWLS SVTRHVRIYA AYIDPVTCEF DQTQMDKLTL
ILDPTNEFVW TSETCNKVYA YFQELVDHYE GAPLTEYTLR LIGSDIEHYI RKLLYDGEIK
YNMNARVLNF SMGKPRILFN DGLPQNVQ
