ID   NDHN_SYNY3              Reviewed;         161 AA.
AC   P74069;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=NAD(P)H-quinone oxidoreductase subunit N;
DE            EC=7.1.1.-;
DE   AltName: Full=NAD(P)H dehydrogenase I subunit N;
DE            Short=NDH-1 subunit N;
DE            Short=NDH-N;
GN   Name=ndhN; OrderedLocusNames=sll1262;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-8, CHARACTERIZATION AS A MEMBER OF THE
RP   NAD(P)H-QUINONE OXIDOREDUCTASE COMPLEX, AND SUBCOMPLEXES OF NDH-1.
RX   PubMed=15102833; DOI=10.1074/jbc.m401107200;
RA   Prommeenate P., Lennon A.M., Markert C., Hippler M., Nixon P.J.;
RT   "Subunit composition of NDH-1 complexes of Synechocystis sp. PCC 6803:
RT   identification of two new ndh gene products with nuclear-encoded homologues
RT   in the chloroplast Ndh complex.";
RL   J. Biol. Chem. 279:28165-28173(2004).
RN   [3]
RP   PROTEIN SEQUENCE OF 16-36; 43-70; 78-107 AND 139-147, AND SUBCOMPLEXES OF
RP   NDH-1.
RX   PubMed=15548534; DOI=10.1074/jbc.m410914200;
RA   Battchikova N., Zhang P., Rudd S., Ogawa T., Aro E.-M.;
RT   "Identification of NdhL and Ssl1690 (NdhO) in NDH-1L and NDH-1M complexes
RT   of Synechocystis sp. PCC 6803.";
RL   J. Biol. Chem. 280:2587-2595(2005).
CC   -!- FUNCTION: NDH-1 shuttles electrons from an unknown electron donor, via
CC       FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory
CC       and/or the photosynthetic chain. The immediate electron acceptor for
CC       the enzyme in this species is believed to be plastoquinone. Couples the
CC       redox reaction to proton translocation, and thus conserves the redox
CC       energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in
CC       inorganic carbon-concentration (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n
CC         H(+)(out) + NAD(+); Xref=Rhea:RHEA:42608, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:62192;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n
CC         H(+)(out) + NADP(+); Xref=Rhea:RHEA:42612, Rhea:RHEA-COMP:9561,
CC         Rhea:RHEA-COMP:9562, ChEBI:CHEBI:15378, ChEBI:CHEBI:17757,
CC         ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:62192;
CC   -!- SUBUNIT: NDH-1 can be composed of about 15 different subunits;
CC       different subcomplexes with different compositions have been identified
CC       which probably have different functions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000305};
CC       Peripheral membrane protein {ECO:0000305}; Cytoplasmic side
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the complex I NdhN subunit family.
CC       {ECO:0000305}.
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DR   EMBL; BA000022; BAA18145.1; -; Genomic_DNA.
DR   PIR; S75584; S75584.
DR   AlphaFoldDB; P74069; -.
DR   SMR; P74069; -.
DR   IntAct; P74069; 5.
DR   STRING; 1148.1653230; -.
DR   PaxDb; P74069; -.
DR   EnsemblBacteria; BAA18145; BAA18145; BAA18145.
DR   KEGG; syn:sll1262; -.
DR   eggNOG; ENOG502ZBMI; Bacteria.
DR   InParanoid; P74069; -.
DR   OMA; HGIRPPH; -.
DR   PhylomeDB; P74069; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IEA:UniProtKB-UniRule.
DR   GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR   HAMAP; MF_01353; NDH1_NDH1N; 1.
DR   InterPro; IPR020874; NAD(P)H-quinone_OxRdtase_su_N.
DR   PANTHER; PTHR35515; PTHR35515; 1.
DR   Pfam; PF11909; NdhN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Membrane; NAD; NADP; Plastoquinone; Quinone;
KW   Reference proteome; Thylakoid; Translocase; Transport.
FT   CHAIN           1..161
FT                   /note="NAD(P)H-quinone oxidoreductase subunit N"
FT                   /id="PRO_0000352243"
SQ   SEQUENCE   161 AA;  17630 MW;  92E8953D18192973 CRC64;
     MLPLPLIANG KGFIRALEND GALAVYAPLE GGYEGRYQRR LRANGYASIS LSARGLGDVE
     AYLMQVHGVR PAHLGKKNIA QEGAVGPIYF AQPIAGYQLE NLPAQSKGLV LWILEGYILS
     QTEIQDLISL TKRVPKLKVV LEMGGDRVFR WQPLLDCLQA A