ID   NDR1B_XENLA             Reviewed;         396 AA.
AC   Q7ZWV3;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Protein NDRG1-B;
DE            Short=xNDRG1-B;
GN   Name=ndrg1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1] {ECO:0000312|EMBL:AAH46693.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000312|EMBL:AAH46693.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in pronephros development, after
CC       specification of the pronephros. {ECO:0000250|UniProtKB:Q641F2}.
CC   -!- SIMILARITY: Belongs to the NDRG family. {ECO:0000255}.
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DR   EMBL; BC046693; AAH46693.1; -; mRNA.
DR   RefSeq; NP_001080627.1; NM_001087158.1.
DR   AlphaFoldDB; Q7ZWV3; -.
DR   SMR; Q7ZWV3; -.
DR   ESTHER; xenla-ndr1b; Ndr_family.
DR   MEROPS; S33.988; -.
DR   DNASU; 380319; -.
DR   GeneID; 380319; -.
DR   KEGG; xla:380319; -.
DR   CTD; 380319; -.
DR   Xenbase; XB-GENE-993278; ndrg1.S.
DR   OMA; MFIDSYI; -.
DR   OrthoDB; 854690at2759; -.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 380319; Expressed in camera-type eye and 13 other tissues.
DR   GO; GO:0045576; P:mast cell activation; IEA:InterPro.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:InterPro.
DR   GO; GO:0048793; P:pronephros development; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell population proliferation; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004142; NDRG.
DR   InterPro; IPR030693; NDRG1.
DR   PANTHER; PTHR11034; PTHR11034; 1.
DR   PANTHER; PTHR11034:SF18; PTHR11034:SF18; 1.
DR   Pfam; PF03096; Ndr; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Reference proteome; Repeat.
FT   CHAIN           1..396
FT                   /note="Protein NDRG1-B"
FT                   /id="PRO_0000232426"
FT   REPEAT          340..349
FT                   /note="1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          350..359
FT                   /note="2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          360..369
FT                   /note="3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          370..379
FT                   /note="4"
FT                   /evidence="ECO:0000255"
FT   REGION          326..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..379
FT                   /note="4 X 10 AA tandem repeats of G-[NS]-R-S-R-[AS]-[HQ]-
FT                   T-[DGN]-[DET]"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        326..364
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..396
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   396 AA;  43505 MW;  60DB4829A4D41548 CRC64;
     MSAEMTDLNF AEGRPLMGEK EDDITVLLQE YVTQEHDIET AHGIVHVTMC GTPKLNRPVI
     LTYHDIGLNH KTCFNSLFNF EDMHEITQHF SVCHVDAPGQ QEGAASFPAG YMYPSMDQLA
     EMLPGVVQQL GLKSIIGLGI GSGAYILTRF ALNHPSMVEG LVLININPCA EGWMDWAATK
     ISGWAHALPE MVISHLFSKD EVHSNPELVE TYRQHILHDI NQNNLQLFVK SYNSRRDLEI
     ERPIPGSNTV TLKCPSLLVV GDSSPAVDAV VECNSKLDPT KTTLLKMSDC GGFPQVVQPA
     KLAEAFKYFV QGMGYMPAAS MTRLMRSRTG SAASSSSQDG NRSRSHTNEG SRSRSQTGDG
     NRSRAHTGDG NRSRSHTDTN NVNSDHNTPK SMEVSC