ID   NDRG3_BOVIN             Reviewed;         375 AA.
AC   A7MB28;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Protein NDRG3;
DE   AltName: Full=N-myc downstream-regulated gene 3 protein;
GN   Name=NDRG3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NDRG family. {ECO:0000305}.
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DR   EMBL; BC151302; AAI51303.1; -; mRNA.
DR   RefSeq; NP_001095466.1; NM_001101996.1.
DR   AlphaFoldDB; A7MB28; -.
DR   SMR; A7MB28; -.
DR   STRING; 9913.ENSBTAP00000026141; -.
DR   ESTHER; bovin-ndrg3; Ndr_family.
DR   PaxDb; A7MB28; -.
DR   PRIDE; A7MB28; -.
DR   Ensembl; ENSBTAT00000026141; ENSBTAP00000026141; ENSBTAG00000019621.
DR   GeneID; 514399; -.
DR   KEGG; bta:514399; -.
DR   CTD; 57446; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019621; -.
DR   VGNC; VGNC:31940; NDRG3.
DR   eggNOG; KOG2931; Eukaryota.
DR   GeneTree; ENSGT00950000182872; -.
DR   HOGENOM; CLU_035361_1_0_1; -.
DR   InParanoid; A7MB28; -.
DR   OrthoDB; 854690at2759; -.
DR   TreeFam; TF313168; -.
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000019621; Expressed in retina and 103 other tissues.
DR   ExpressionAtlas; A7MB28; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004142; NDRG.
DR   InterPro; IPR030692; NDRG3.
DR   PANTHER; PTHR11034; PTHR11034; 1.
DR   PANTHER; PTHR11034:SF20; PTHR11034:SF20; 1.
DR   Pfam; PF03096; Ndr; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Phosphoprotein; Reference proteome.
FT   CHAIN           1..375
FT                   /note="Protein NDRG3"
FT                   /id="PRO_0000357052"
FT   REGION          327..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         322
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         329
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         331
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         332
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         334
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         335
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         338
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         341
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         352
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         355
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         361
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9QYF9"
FT   MOD_RES         374
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
SQ   SEQUENCE   375 AA;  41252 MW;  149B08AEADB61778 CRC64;
     MDELQDVQLT EIKPLLNDKN GTRNFQDFDC QEHDIETAHG MVHVTIRGLP KGNRPVILTY
     HDIGLNHKSC FNAFFNFEDM QEITQHFAVC HVDAPGQQEG APSFPTGYQY PTMDELAEML
     PPVLTHLNLK SIIGIGVGAG AYILSRFALN HPELVEGLVL INVDPCAKGW IDWAASKLSG
     LTTNVVDIIL SHHFGQEELQ ANLDLIQTYR LHIAQDINQE NLQLFLGSYN GRKDLEIERP
     ILGQNDNKSK TLKCSTLLVV GDSSPAVEAV VECNSRLNPV NTTLLKMADC GGLPQVVQPG
     KLTEAFKYFL QGMGYIPSAS MTRLARSRTH STSSSIGSGE SAFSRSVASN QSDGTQESSE
     SPDVLDRHQT MEVSC