ID   NDRG3_PONAB             Reviewed;         375 AA.
AC   Q5RA95;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Protein NDRG3;
DE   AltName: Full=N-myc downstream-regulated gene 3 protein;
GN   Name=NDRG3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NDRG family. {ECO:0000305}.
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DR   EMBL; CR859123; CAH91315.1; -; mRNA.
DR   RefSeq; NP_001125778.1; NM_001132306.2.
DR   AlphaFoldDB; Q5RA95; -.
DR   SMR; Q5RA95; -.
DR   STRING; 9601.ENSPPYP00000012256; -.
DR   ESTHER; ponpy-q5ra95; Ndr_family.
DR   MEROPS; S33.987; -.
DR   Ensembl; ENSPPYT00000012737; ENSPPYP00000012256; ENSPPYG00000010974.
DR   GeneID; 100172705; -.
DR   KEGG; pon:100172705; -.
DR   CTD; 57446; -.
DR   eggNOG; KOG2931; Eukaryota.
DR   GeneTree; ENSGT00950000182872; -.
DR   HOGENOM; CLU_035361_1_0_1; -.
DR   InParanoid; Q5RA95; -.
DR   OMA; SQWEYFI; -.
DR   OrthoDB; 854690at2759; -.
DR   TreeFam; TF313168; -.
DR   Proteomes; UP000001595; Chromosome 20.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004142; NDRG.
DR   InterPro; IPR030692; NDRG3.
DR   PANTHER; PTHR11034; PTHR11034; 1.
DR   PANTHER; PTHR11034:SF20; PTHR11034:SF20; 1.
DR   Pfam; PF03096; Ndr; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Phosphoprotein; Reference proteome.
FT   CHAIN           1..375
FT                   /note="Protein NDRG3"
FT                   /id="PRO_0000357053"
FT   REGION          326..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         322
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         329
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         331
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         332
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         334
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         335
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         338
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         341
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         352
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         355
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
FT   MOD_RES         361
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9QYF9"
FT   MOD_RES         374
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9UGV2"
SQ   SEQUENCE   375 AA;  41425 MW;  012B725B2FC5F476 CRC64;
     MDELQDVQLT EIKPLLNDKN GTRNFQDFDC QEHDIETTHG MVHVTIRGLP KGNRPVILTY
     HDIGLNHKSC FNAFFNFEDM QEITQHFAVC HVDAPGQQEG APSFPTGYQY PTMDELAEML
     PPVLTHLSLK SIIGIGVGAG AYILSRFALN HPELVEGLVL INVDPCAKGW IDWAASKLSG
     LTTNVVDIIL AHHFGQEELQ ANPDLIQTYR MHIAQDINQD NLQLFLNSYN GRRDLEIERP
     ILGQNDNKSK TLKCSTLLVV GDNSPAVEAV VECNSRLNPI NTTLLKMADC GGLPQVVQPG
     KLTEAFKYFL QGMGYIPSAS MTRLARSRTH STSSSLGSGE SPFSRSVTSN QSDGTQESCE
     SPDVLDRHQT MEVSC