NDUA2_ARATH
ID NDUA2_ARATH Reviewed; 97 AA.
AC Q9FIJ2;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2;
GN OrderedLocusNames=At5g47890; ORFNames=MCA23_23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of at least 49 different subunits.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA2 subunit family.
CC {ECO:0000305}.
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DR EMBL; AB016886; BAB11336.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95585.1; -; Genomic_DNA.
DR EMBL; AY065304; AAL38780.1; -; mRNA.
DR EMBL; AY096432; AAM20072.1; -; mRNA.
DR EMBL; AY087919; AAM65469.1; -; mRNA.
DR RefSeq; NP_199600.1; NM_124163.5.
DR PDB; 7A23; EM; 3.70 A; Q=1-97.
DR PDB; 7A24; EM; 3.80 A; Q=1-97.
DR PDB; 7AQR; EM; 2.91 A; S=1-97.
DR PDB; 7AR7; EM; 3.72 A; S=2-94.
DR PDB; 7AR8; EM; 3.53 A; S=1-97.
DR PDB; 7ARB; EM; 3.41 A; S=1-97.
DR PDBsum; 7A23; -.
DR PDBsum; 7A24; -.
DR PDBsum; 7AQR; -.
DR PDBsum; 7AR7; -.
DR PDBsum; 7AR8; -.
DR PDBsum; 7ARB; -.
DR AlphaFoldDB; Q9FIJ2; -.
DR SMR; Q9FIJ2; -.
DR BioGRID; 20088; 3.
DR IntAct; Q9FIJ2; 1.
DR STRING; 3702.AT5G47890.1; -.
DR TCDB; 3.D.1.6.3; the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.
DR PaxDb; Q9FIJ2; -.
DR PRIDE; Q9FIJ2; -.
DR ProteomicsDB; 251131; -.
DR EnsemblPlants; AT5G47890.1; AT5G47890.1; AT5G47890.
DR GeneID; 834840; -.
DR Gramene; AT5G47890.1; AT5G47890.1; AT5G47890.
DR KEGG; ath:AT5G47890; -.
DR Araport; AT5G47890; -.
DR TAIR; locus:2160882; AT5G47890.
DR eggNOG; KOG3446; Eukaryota.
DR HOGENOM; CLU_110897_1_0_1; -.
DR InParanoid; Q9FIJ2; -.
DR OMA; PILICKC; -.
DR OrthoDB; 1633416at2759; -.
DR PhylomeDB; Q9FIJ2; -.
DR PRO; PR:Q9FIJ2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FIJ2; baseline and differential.
DR Genevisible; Q9FIJ2; AT.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR InterPro; IPR016464; NADH_Ub_cplx-1_asu_su-2.
DR InterPro; IPR007741; Ribosome/NADH_DH.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12878; PTHR12878; 1.
DR Pfam; PF05047; L51_S25_CI-B8; 1.
DR PIRSF; PIRSF005822; NDUA2; 1.
DR SMART; SM00916; L51_S25_CI-B8; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Disulfide bond; Electron transport; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW Transport.
FT CHAIN 1..97
FT /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT subunit 2"
FT /id="PRO_0000410931"
FT DISULFID 19..53
FT /note="Redox-active"
FT /evidence="ECO:0000250"
FT HELIX 3..5
FT /evidence="ECO:0007829|PDB:7AQR"
FT HELIX 7..10
FT /evidence="ECO:0007829|PDB:7AQR"
FT STRAND 12..21
FT /evidence="ECO:0007829|PDB:7AQR"
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:7AQR"
FT HELIX 26..42
FT /evidence="ECO:0007829|PDB:7AQR"
FT STRAND 48..55
FT /evidence="ECO:0007829|PDB:7AQR"
FT STRAND 59..63
FT /evidence="ECO:0007829|PDB:7AQR"
FT HELIX 79..93
FT /evidence="ECO:0007829|PDB:7AQR"
SQ SEQUENCE 97 AA; 10851 MW; B7D2ECD546363CEB CRC64;
MAWRGSISKS MKELRILLCQ SSPASAPTRT FVEKNYKDLK SLNPKLPILI RECSGVQPQM
WARYDMGVER CVNLDGLTEP QILKALENLV KSGATKA
