NDUA3_PANTR
ID NDUA3_PANTR Reviewed; 84 AA.
AC Q0MQ96;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3;
DE AltName: Full=Complex I-B9;
DE Short=CI-B9;
DE AltName: Full=NADH-ubiquinone oxidoreductase B9 subunit;
GN Name=NDUFA3;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA Wallace D.C.;
RT "Adaptive selection of mitochondrial complex I subunits during primate
RT radiation.";
RL Gene 378:11-18(2006).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000250|UniProtKB:O95167}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000250|UniProtKB:O95167}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:O95167}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA3 subunit family.
CC {ECO:0000305}.
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DR EMBL; DQ885738; ABH12247.1; -; mRNA.
DR RefSeq; NP_001238904.1; NM_001251975.1.
DR RefSeq; XP_016792292.1; XM_016936803.1.
DR AlphaFoldDB; Q0MQ96; -.
DR SMR; Q0MQ96; -.
DR STRING; 9598.ENSPTRP00000048498; -.
DR PaxDb; Q0MQ96; -.
DR Ensembl; ENSPTRT00000055898; ENSPTRP00000048498; ENSPTRG00000028890.
DR Ensembl; ENSPTRT00000091275; ENSPTRP00000093938; ENSPTRG00000045461.
DR GeneID; 100614219; -.
DR KEGG; ptr:100614219; -.
DR CTD; 4696; -.
DR VGNC; VGNC:11198; NDUFA3.
DR eggNOG; ENOG502S4RS; Eukaryota.
DR GeneTree; ENSGT00390000004322; -.
DR HOGENOM; CLU_171491_0_0_1; -.
DR InParanoid; Q0MQ96; -.
DR OMA; PDIPAHP; -.
DR OrthoDB; 1577370at2759; -.
DR TreeFam; TF333021; -.
DR Proteomes; UP000002277; Chromosome 19.
DR Bgee; ENSPTRG00000028890; Expressed in hindlimb stylopod muscle and 21 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR026626; NDUFA3.
DR PANTHER; PTHR15221; PTHR15221; 1.
DR Pfam; PF14987; NADHdh_A3; 1.
PE 3: Inferred from homology;
KW Acetylation; Electron transport; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW Transmembrane; Transmembrane helix; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q02371"
FT CHAIN 2..84
FT /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT subunit 3"
FT /id="PRO_0000251801"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 56..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q02371"
SQ SEQUENCE 84 AA; 9279 MW; 38B27A96D7A05D31 CRC64;
MAARVGAFLK NAWDKEPVLV VSFVVGGLAV ILPPLSPYFK YSVMINKATP YNYPVPVRDD
GNMPDVPSHP QDPQGPSLEW LKKL
