NDUA5_CAEEL
ID NDUA5_CAEEL Reviewed; 150 AA.
AC Q18359;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5;
GN ORFNames=C33A12.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA5 subunit family.
CC {ECO:0000305}.
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DR EMBL; Z68493; CAA92789.1; -; Genomic_DNA.
DR PIR; T19659; T19659.
DR RefSeq; NP_501688.1; NM_069287.4.
DR AlphaFoldDB; Q18359; -.
DR SMR; Q18359; -.
DR BioGRID; 42891; 36.
DR STRING; 6239.C33A12.1; -.
DR EPD; Q18359; -.
DR PaxDb; Q18359; -.
DR PeptideAtlas; Q18359; -.
DR PRIDE; Q18359; -.
DR EnsemblMetazoa; C33A12.1.1; C33A12.1.1; WBGene00007880.
DR GeneID; 177786; -.
DR KEGG; cel:CELE_C33A12.1; -.
DR UCSC; C33A12.1; c. elegans.
DR CTD; 177786; -.
DR WormBase; C33A12.1; CE05347; WBGene00007880; -.
DR eggNOG; KOG3365; Eukaryota.
DR GeneTree; ENSGT00390000008099; -.
DR HOGENOM; CLU_099943_2_0_1; -.
DR InParanoid; Q18359; -.
DR OMA; VNEHPHR; -.
DR OrthoDB; 1372253at2759; -.
DR PhylomeDB; Q18359; -.
DR Reactome; R-CEL-6799198; Complex I biogenesis.
DR PRO; PR:Q18359; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00007880; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:WormBase.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IC:WormBase.
DR GO; GO:0022904; P:respiratory electron transport chain; IBA:GO_Central.
DR InterPro; IPR006806; NDUFA5.
DR PANTHER; PTHR12653; PTHR12653; 1.
DR Pfam; PF04716; ETC_C1_NDUFA5; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transport.
FT CHAIN 1..150
FT /note="Probable NADH dehydrogenase [ubiquinone] 1 alpha
FT subcomplex subunit 5"
FT /id="PRO_0000118636"
SQ SEQUENCE 150 AA; 17335 MW; 170C88D605874EF1 CRC64;
MSSRFLRTAV ARATQQRSMY ENPYINRFKA RSKVSEDFHK KTTGITGLFV NEHPHRALTV
VYGRILRALE QIPRDAAYRK YTEAVVKQRL ALVQAENDIK KLEEKIGMGQ IEEVIEQAEY
ELETTRAIVD SKAWEPLVES APKGQWSWPV