ID   NDUA5_DICDI             Reviewed;         117 AA.
AC   Q559Z4; Q86IM2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5;
GN   Name=ndufa5; ORFNames=DDB_G0272394;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Complex I is composed of about 45 different subunits.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA5 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000008; EAL71349.1; -; Genomic_DNA.
DR   RefSeq; XP_645190.1; XM_640098.1.
DR   AlphaFoldDB; Q559Z4; -.
DR   SMR; Q559Z4; -.
DR   STRING; 44689.DDB0233240; -.
DR   PaxDb; Q559Z4; -.
DR   EnsemblProtists; EAL71349; EAL71349; DDB_G0272394.
DR   GeneID; 8618362; -.
DR   KEGG; ddi:DDB_G0272394; -.
DR   dictyBase; DDB_G0272394; ndufa5.
DR   eggNOG; KOG3365; Eukaryota.
DR   HOGENOM; CLU_099943_0_1_1; -.
DR   InParanoid; Q559Z4; -.
DR   OMA; VNEHPHR; -.
DR   PhylomeDB; Q559Z4; -.
DR   PRO; PR:Q559Z4; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:dictyBase.
DR   GO; GO:0022904; P:respiratory electron transport chain; IBA:GO_Central.
DR   InterPro; IPR006806; NDUFA5.
DR   PANTHER; PTHR12653; PTHR12653; 1.
DR   Pfam; PF04716; ETC_C1_NDUFA5; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transport.
FT   CHAIN           1..117
FT                   /note="Probable NADH dehydrogenase [ubiquinone] 1 alpha
FT                   subcomplex subunit 5"
FT                   /id="PRO_0000328290"
SQ   SEQUENCE   117 AA;  13200 MW;  7412F306D12CB9E1 CRC64;
     MSIHLIKKST GITGLKVEPN ARHILAGLYN QLLKKLEILP PTAGYRKSAE LETKFRLGVI
     ENETDIVKIE NKIYAGQIEE LIVQAKNDLK VVDLVHESRA WELPDKNKPP VVIYSSK