ID   NDUA6_DICDI             Reviewed;         124 AA.
AC   Q54F42;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;
GN   Name=ndufa6; ORFNames=DDB_G0291129;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed to be not
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral membrane
CC       protein; Matrix side.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR   EMBL; AAFI02000175; EAL61848.1; -; Genomic_DNA.
DR   RefSeq; XP_635348.1; XM_630256.1.
DR   AlphaFoldDB; Q54F42; -.
DR   SMR; Q54F42; -.
DR   STRING; 44689.DDB0233241; -.
DR   PaxDb; Q54F42; -.
DR   EnsemblProtists; EAL61848; EAL61848; DDB_G0291129.
DR   GeneID; 8627996; -.
DR   KEGG; ddi:DDB_G0291129; -.
DR   dictyBase; DDB_G0291129; ndufa6.
DR   eggNOG; KOG3426; Eukaryota.
DR   HOGENOM; CLU_2008226_0_0_1; -.
DR   InParanoid; Q54F42; -.
DR   OMA; RSHVVNY; -.
DR   PhylomeDB; Q54F42; -.
DR   PRO; PR:Q54F42; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; ISS:dictyBase.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   InterPro; IPR016488; NADH_Ub_cplx-1_asu_su-6.
DR   PANTHER; PTHR12964; PTHR12964; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transport.
FT   CHAIN           1..124
FT                   /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT                   subunit 6"
FT                   /id="PRO_0000327576"
SQ   SEQUENCE   124 AA;  14793 MW;  00A963C889765100 CRC64;
     MSSNMQAMKQ MRPALVSLTQ QQARRRCFKL YRNCIRSIPH LIQHYNLSYN MSEMRNRFRS
     NFVEFEEVTE KNQLDRLAFI GETELFDAMS LLKTRSHVVN YFDTQPVNAK TISESEKLLN
     NFFE