ID   NDUA6_PONPY             Reviewed;         128 AA.
AC   Q0MQA3;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 {ECO:0000250|UniProtKB:P56556};
DE   AltName: Full=Complex I-B14;
DE            Short=CI-B14;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B14 subunit;
GN   Name=NDUFA6 {ECO:0000250|UniProtKB:P56556};
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed to be not
CC       involved in catalysis. Required for proper complex I assembly. Complex
CC       I functions in the transfer of electrons from NADH to the respiratory
CC       chain. The immediate electron acceptor for the enzyme is believed to be
CC       ubiquinone. {ECO:0000250|UniProtKB:P56556}.
CC   -!- SUBUNIT: Mammalian complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:P56556}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P56556}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P56556}; Matrix side
CC       {ECO:0000250|UniProtKB:P56556}.
CC   -!- SIMILARITY: Belongs to the complex I LYR family. {ECO:0000305}.
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DR   EMBL; DQ885731; ABH12240.1; -; mRNA.
DR   AlphaFoldDB; Q0MQA3; -.
DR   SMR; Q0MQA3; -.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   CDD; cd20266; Complex1_LYR_NDUFA6_LYRM6; 1.
DR   InterPro; IPR008011; Complex1_LYR_dom.
DR   InterPro; IPR045299; Complex1_LYR_NDUFA6_LYRM6.
DR   InterPro; IPR016488; NADH_Ub_cplx-1_asu_su-6.
DR   PANTHER; PTHR12964; PTHR12964; 1.
DR   Pfam; PF05347; Complex1_LYR; 1.
DR   PIRSF; PIRSF006643; NDUA6; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Phosphoprotein; Respiratory chain; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q02366"
FT   CHAIN           2..128
FT                   /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT                   subunit 6"
FT                   /id="PRO_0000251169"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q02366"
FT   MOD_RES         11
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P56556"
SQ   SEQUENCE   128 AA;  15064 MW;  ABE60B277C55A121 CRC64;
     MAGSGVRQAA STASTFVKPI FSRDMNEAKR RVRELYRAWY REVPNTVHQF QLDITVKMGR
     DKVREMFMKN AHVTDPRVVD LLVIKGKIEL EETINVWKQQ THVMRFFHET EAPRPKDFLS
     KFYVGHDP