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NDUAC_CAEEL
ID   NDUAC_CAEEL             Reviewed;         146 AA.
AC   Q9N2W7;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 17.0 kDa subunit;
GN   ORFNames=Y94H6A.8;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA12 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; FO081810; CCD74208.1; -; Genomic_DNA.
DR   RefSeq; NP_500247.2; NM_067846.4.
DR   AlphaFoldDB; Q9N2W7; -.
DR   SMR; Q9N2W7; -.
DR   BioGRID; 42202; 58.
DR   STRING; 6239.Y94H6A.8.2; -.
DR   EPD; Q9N2W7; -.
DR   PaxDb; Q9N2W7; -.
DR   PeptideAtlas; Q9N2W7; -.
DR   EnsemblMetazoa; Y94H6A.8.1; Y94H6A.8.1; WBGene00022380.
DR   GeneID; 177056; -.
DR   KEGG; cel:CELE_Y94H6A.8; -.
DR   UCSC; Y94H6A.8.1; c. elegans.
DR   CTD; 177056; -.
DR   WormBase; Y94H6A.8; CE39995; WBGene00022380; -.
DR   eggNOG; KOG3382; Eukaryota.
DR   GeneTree; ENSGT00390000005848; -.
DR   HOGENOM; CLU_110455_1_1_1; -.
DR   InParanoid; Q9N2W7; -.
DR   OMA; WHGWIHH; -.
DR   OrthoDB; 1475919at2759; -.
DR   PhylomeDB; Q9N2W7; -.
DR   PRO; PR:Q9N2W7; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00022380; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; HDA:WormBase.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   InterPro; IPR007763; NDUFA12.
DR   PANTHER; PTHR12910; PTHR12910; 1.
DR   Pfam; PF05071; NDUFA12; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transport.
FT   CHAIN           1..146
FT                   /note="Probable NADH dehydrogenase [ubiquinone] 1 alpha
FT                   subcomplex subunit 12"
FT                   /id="PRO_0000118847"
SQ   SEQUENCE   146 AA;  17073 MW;  0A8549D622977786 CRC64;
     MSLKAWLGID KIQKFGQMVK EIGGVKAVLK KRYLMDATRV GTLVGSDNFG NRYYENNAYF
     VPRNRWVEFP DKVWLDYDAT QVPPEWHSWL HHITDDAPSV KPPPTQDWVL EHKENTSIYA
     DKKYVPYSTT RTKIQGWQPG EKPQFD
 
 
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