ID   NDUAC_GORGO             Reviewed;         145 AA.
AC   Q0MQ86;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;
DE   AltName: Full=Complex I-B17.2;
DE            Short=CI-B17.2;
DE            Short=CIB17.2;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B17.2;
GN   Name=NDUFA12;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9UI09}; Peripheral membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA12 subunit family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ885748; ABH12257.1; -; mRNA.
DR   RefSeq; NP_001266545.1; NM_001279616.1.
DR   AlphaFoldDB; Q0MQ86; -.
DR   SMR; Q0MQ86; -.
DR   STRING; 9593.ENSGGOP00000012562; -.
DR   Ensembl; ENSGGOT00000012924; ENSGGOP00000012562; ENSGGOG00000012880.
DR   GeneID; 101148753; -.
DR   KEGG; ggo:101148753; -.
DR   CTD; 55967; -.
DR   eggNOG; KOG3382; Eukaryota.
DR   GeneTree; ENSGT00390000005848; -.
DR   HOGENOM; CLU_110455_1_0_1; -.
DR   InParanoid; Q0MQ86; -.
DR   OrthoDB; 1475919at2759; -.
DR   Proteomes; UP000001519; Chromosome 12.
DR   Bgee; ENSGGOG00000012880; Expressed in heart and 6 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IEA:Ensembl.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   InterPro; IPR007763; NDUFA12.
DR   PANTHER; PTHR12910; PTHR12910; 1.
DR   Pfam; PF05071; NDUFA12; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW   Transport.
FT   CHAIN           1..145
FT                   /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT                   subunit 12"
FT                   /id="PRO_0000251817"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:O97725"
SQ   SEQUENCE   145 AA;  17147 MW;  C76C7F2F43C504F9 CRC64;
     MELVQVLKRG LQQITGHGGL RGYLRVFFRT NDAKVGTLVG EDKYGNKYYE DNKQFFGRHR
     WVVYTTEMNG KNTFWDVDGS MVPPEWHRWL HSMTDDPPTT KPLTARKFIW TNHKFNMTGT
     PEQYVPYSTT RKKIQEWIPP STPYK