ID   NDUAC_PONPY             Reviewed;         145 AA.
AC   Q0MQ85;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;
DE   AltName: Full=Complex I-B17.2;
DE            Short=CI-B17.2;
DE            Short=CIB17.2;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B17.2;
GN   Name=NDUFA12;
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9UI09}; Peripheral membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:Q9UI09}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA12 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885749; ABH12258.1; -; mRNA.
DR   AlphaFoldDB; Q0MQ85; -.
DR   SMR; Q0MQ85; -.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR   InterPro; IPR007763; NDUFA12.
DR   PANTHER; PTHR12910; PTHR12910; 1.
DR   Pfam; PF05071; NDUFA12; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Respiratory chain; Transport.
FT   CHAIN           1..145
FT                   /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT                   subunit 12"
FT                   /id="PRO_0000251819"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:O97725"
SQ   SEQUENCE   145 AA;  17105 MW;  737666E0456AC098 CRC64;
     MELVQVLKRG LQRITGHGGL RGYLRVFFRT NDAKVGTLVG EDKYGNKYYE DNKQFFGRHR
     WVVYTTEMNG KNTFWDVDGS MVPPEWHHWL HSITDDPPTT KPLTARKFIW TNHKFNVTGT
     PEQYVPYSTT RKKIQEWIPP STPYK