NDUAD_DICDI
ID NDUAD_DICDI Reviewed; 113 AA.
AC Q86IZ2; Q555X1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13;
GN Name=ndufa13; ORFNames=DDB_G0274311;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of about 45 different subunits.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA13 subunit family.
CC {ECO:0000305}.
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DR EMBL; AAFI02000012; EAL70048.1; -; Genomic_DNA.
DR RefSeq; XP_643939.1; XM_638847.1.
DR AlphaFoldDB; Q86IZ2; -.
DR SMR; Q86IZ2; -.
DR STRING; 44689.DDB0238775; -.
DR PaxDb; Q86IZ2; -.
DR EnsemblProtists; EAL70048; EAL70048; DDB_G0274311.
DR GeneID; 8619367; -.
DR KEGG; ddi:DDB_G0274311; -.
DR dictyBase; DDB_G0274311; -.
DR eggNOG; ENOG502RIAU; Eukaryota.
DR HOGENOM; CLU_2138201_0_0_1; -.
DR InParanoid; Q86IZ2; -.
DR OMA; ENDIMFL; -.
DR PhylomeDB; Q86IZ2; -.
DR PRO; PR:Q86IZ2; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR InterPro; IPR009346; GRIM-19.
DR PANTHER; PTHR12966; PTHR12966; 1.
DR Pfam; PF06212; GRIM-19; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..113
FT /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT subunit 13"
FT /id="PRO_0000328478"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 113 AA; 12894 MW; 996243B5C6A3EDA1 CRC64;
MVGYRQKWVQ DLPPAGGFPK LKYARTSTSP IPGAYIFAGV FSIMAVGTYI FFSDKVERNA
REEEEKRRLS MILPILQAEN DINFLASPHQ NVYFTRWMPP QTGKRAAALL RDL